Postdoctoral Scientist — Cytokine‑Mediated Cancer Cell Death

Servier; Palaiseau; Remote; EUR 42,000 - 54,000; Full time

Benefits offered by this job

13th month salary

Profit-sharing / employee participate.

Transportation allowance

27 days paid leave + 23 RTT

Flexible remote work options depending

On-site restaurant and CSE activities

Job summary

Servier invites applications for a three-year Postdoctoral fellow in Cytokine induced cell death at the Paris-Saclay R&D Institute. The project explores How colorectal cancer cells resist immune cytokine pressure and aims to enhance cytokine-induced tumor-cell killing using mechanistic biology, functional genomics and translational models.

The candidate will work in a collaborative, multi-disciplinary team, applying cutting-edge techniques in cell biology and translational cancer research to

Qualifications

• PhD in cancer biology, tumor immunology, cell-death biology, molecular biology, functional genomics or a related discipline.
• Experience with oncology models and/or cytokine signaling is an advantage.
• Expertise in mammalian cell culture and quantitative cell-based assays.
• Experience with cancer cell models and with one or more of the following: CRISPR-based perturbation or screening, flow cytometry, immunoblotting, or analysis of signaling and cell-death pathways.
• Experience with organoids or patient-derived models is a plus.
• Excellent written and oral English.
• Ability to drive a research project with scientific independence, organize priorities, collaborate effectively in multidisciplinary teams, and communicate results clearly to scientific and project stakeholders.
• Autonomous, proactive, rigorous, collaborative and innovative.

Responsibilities

• Design and execute in vitro and in vivo experiments to advance the research project.
• Analyze and interpret data and define next steps.
• Review literature and integrate findings into decisions.
• Present progress at internal meetings.
• Manage priorities, timelines and resources for project execution.
• Collaborate across Immuno-Oncology programs and share learnings.
• Identify and evaluate potential therapeutic targets.

Skills

PhD in cancer biology

Cytokine signaling

Mammalian cell culture

CRISPR perturbation

Flow cytometry

Immunoblotting

Organoid models

English proficiency

Education

PhD in cancer biology or related

Tools

CRISPR-based perturbation

Job description

Servier invites applications for a three-year Postdoctoral fellow in Cytokine induced cell death at the Paris-Saclay R&D Institute. The project explores How colorectal cancer cells resist immune cytokine pressure and aims to enhance cytokine-induced tumor-cell killing using mechanistic biology, functional genomics and translational models.

The candidate will work in a collaborative, multi-disciplinary team, applying cutting-edge techniques in cell biology and translational cancer research to