Postdoctoral Researcher - Molecular Study of UPC1 (M/F)

EURAXESS Ireland; Paris; Hybrid; EUR 34,000 - 52,000; Full time

Job summary

CNRS, Biochimie des protéines membranaires, Paris, invites applications for a temporary researcher to study overexpressed UCP1 mutants using biochemical and cell biology approaches. The role combines protein purification, cryo-EM structure determination, and molecular dynamics with cell-based assays.

Occasional visits to the Cochin Institute are expected as part of collaboration with the CNRS research community. Start date 1 Dec 2026; 35 h/week; fixed-term contract.

Qualifications

• In-depth knowledge of protein biochemistry.
• Proficiency in cell biology techniques.
• Experience with molecular dynamics simulations.
• Experience with fermenter culture and fermentation.
• Familiarity with chromatography systems.
• Experience with national supercomputing centers or HPC resources.
• Strong teamwork and collaboration.
• Ability to write scientific articles.

Responsibilities

• Protein purification.
• Cryo-EM structure determination.
• Molecular dynamics simulations.
• Cell transfection and related assays.
• Metabolic labeling.
• Fluorescence microscopy.
• Occasional visits to the Cochin Institute.

Skills

Protein biochemistry

Cell biology techniques

Molecular dynamics simulations

Fermenter culture

Chromatography systems

National supercomputing centers

Teamwork

Writing scientific articles

Job description

Biological sciences > Biological engineering

Organisation/Company CNRS Department Biochimie des protéines membranaires Research Field Chemistry Physics > Biophysics Biological sciences > Biological engineering Researcher Profile Recognised Researcher (R2) Application Deadline 28 Nov 2026 - 23:59 (UTC) Country France Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 1 Dec 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Study of overexpressed UCP1 mutants using biochemical and cell biology approaches.

• Protein purification
• Cryo-EM structure determination
• Molecular dynamics
• Cell transfection
• Metabolic labeling
• Fluorescence microscopy

Occasional visits to the Cochin Institute

Research Field Biological sciences > Biological engineering Years of Research Experience 1 - 4

Additional Information

Eligibility criteria

• In-depth knowledge of protein biochemistry
• Proficiency in cell biology techniques
• Proficiency in molecular dynamics simulations
• Proficiency in fermenter culture
• Proficiency in chromatography systems
• Proficiency in national supercomputing centers
• Teamwork
• Writing scientific articles