Postdoc: Membrane Protein Biochemistry & Cryo-EM

EURAXESS Ireland; Paris; Hybrid; EUR 34,000 - 52,000; Full time

Job summary

CNRS, Biochimie des protéines membranaires, Paris, invites applications for a temporary researcher to study overexpressed UCP1 mutants using biochemical and cell biology approaches. The role combines protein purification, cryo-EM structure determination, and molecular dynamics with cell-based assays.

Occasional visits to the Cochin Institute are expected as part of collaboration with the CNRS research community. Start date 1 Dec 2026; 35 h/week; fixed-term contract.

Qualifications

• In-depth knowledge of protein biochemistry.
• Proficiency in cell biology techniques.
• Experience with molecular dynamics simulations.
• Experience with fermenter culture and fermentation.
• Familiarity with chromatography systems.
• Experience with national supercomputing centers or HPC resources.
• Strong teamwork and collaboration.
• Ability to write scientific articles.

Responsibilities

• Protein purification.
• Cryo-EM structure determination.
• Molecular dynamics simulations.
• Cell transfection and related assays.
• Metabolic labeling.
• Fluorescence microscopy.
• Occasional visits to the Cochin Institute.

Skills

Protein biochemistry

Cell biology techniques

Molecular dynamics simulations

Fermenter culture

Chromatography systems

National supercomputing centers

Teamwork

Writing scientific articles

Job description

CNRS, Biochimie des protéines membranaires, Paris, invites applications for a temporary researcher to study overexpressed UCP1 mutants using biochemical and cell biology approaches. The role combines protein purification, cryo-EM structure determination, and molecular dynamics with cell-based assays.

Occasional visits to the Cochin Institute are expected as part of collaboration with the CNRS research community. Start date 1 Dec 2026; 35 h/week; fixed-term contract.