Postdoctoral position in bacteriophage engineering

Euraxess; Cergy; Sur place; EUR 38 000 - 52 000; Plein temps

Résumé du poste

CY Cergy Paris Université invites applications for a full-time, 24-month postdoctoral research position starting January 2027 in the ERRMECe laboratory to develop engineered bacteriophages against biofilm-associated Staphylococcus aureus infections.

The role spans phage engineering, biofilm microbiology, and translational anti-infective research, with collaboration across international partners and access to unique phage resources under the PHAGOBOOST project and France 2030 funding.

Qualifications

• PhD in microbiology, molecular microbiology, bioengineering, synthetic biology or related field.
• Strong track record with peer‑reviewed publications.
• Excellent written and oral English.
• Ability to work independently and in a collaborative setting.

Responsabilités

• Identify genetic determinants for stable payload integration while preserving phage fitness.
• Implement bacteriophage genome editing tools.
• Evaluate antibiofilm properties of engineered phages in relevant models.
• Disseminate findings and contribute to project reporting.

Connaissances

Research skills

English communication

Independent work

Publications track record

Formation

PhD in microbiology/molecular biology/bioengineering/synthetic biology

Outils

Phage engineering tools

Molecular biology techniques

Description du poste

Offer Description

A full‑time, 24‑month postdoctoral research position, starting in January 2027, is available in the ERRMECe laboratory (CY Cergy Paris Université, France) to develop genetically engineered bacteriophages against biofilm‑associated Staphylococcus aureus infections. The project aims to establish innovative phage engineering strategies to enhance antibiofilm activity using a unique collection of clinically relevant Silviavirus bacteriophages currently deployed in compassionate‑use programmes in France, providing an exceptional translational framework for the development of next‑generation phage therapeutics.

Research Environment and Funding

The successful candidate will join the ERRMECe laboratory at CY Cergy Paris Université (CYU) and work within a multidisciplinary consortium involving the Centre International de Recherche en Infectiologie (CIRI, Lyon), the Hospices Civils de Lyon (HCL), and BioCIS (CNRS, Université Paris‑Saclay, CYU). The project offers access to unique therapeutic bacteriophage resources and a collaborative environment spanning bacteriophage engineering, biofilm microbiology, phage biology, protein engineering and translational anti‑infective research.

This position is funded through the PHAGOBOOST project, supported by CY Generations under the French Government grant "Investissements d’avenir" France 2030.

Responsibilities

• Identify genetic determinants and engineering strategies that enable stable integration of genetic payloads while preserving phage fitness.
• Implement bacteriophage genetic engineering tools for phage genome editing.
• Evaluate the antibiofilm properties of genetically engineered bacteriophages in relevant experimental models.
• Contribute to dissemination of research findings and project reporting.

Candidate Profile

We are seeking a highly motivated candidate with a PhD in microbiology, molecular microbiology, bioengineering, synthetic biology, or a related discipline.

• A strong research track record, evidenced by peer‑reviewed publications.
• Strong experimental skills in microbiology and molecular microbiology.
• Excellent written and oral communication skills in English.
• The ability to work independently while contributing effectively to a collaborative research environment.

Contact & Applications

Please send a single PDF including a cover letter stating your research interests and motivation, a CV, and contact information for two referees. Applications should be sent to: [e-mail]

Where to Apply

E‑mail: [e-mail]