Postdoc: MTJ Translation & Muscle Biology

Inserm France; Illkirch-Graffenstaden; Sur place; EUR 32 000 - 42 000; Plein temps

Résumé du poste

Inserm France in Illkirch-Graffenstaden invites a student to join our lab studying myotendinous junction translation programs. You will use mouse genetics to generate mutants, analyze phenotypes, and explore the local translatome.

The project includes biochemical pull-downs, mass spectrometry and NGS, plus presenting results at lab meetings and conferences and supervising Master's students. English language required.

Qualifications

• Mouse genetics maintenance, genotyping, histological analyses and imaging.
• Physiological tests for phenotyping muscle function.
• Biochemical skills for mass spectrometry and NGS.

Responsabilités

• Use mouse genetics to generate mutants and dissect their phenotype.
• Investigate the local translatome upon mutating RNA binding proteins and identify their binding partners.
• Biochemical pull-down identification of candidate factors using affinity tag fused UTRs.
• Presentation of the work in lab meetings and conferences.
• Supervising Master students.

Connaissances

Mouse genetics

Physiological tests

Biochemical skills

Formation

Master's degree

Outils

Mass spectrometry

NGS

Description du poste

Inserm France in Illkirch-Graffenstaden invites a student to join our lab studying myotendinous junction translation programs. You will use mouse genetics to generate mutants, analyze phenotypes, and explore the local translatome.

The project includes biochemical pull-downs, mass spectrometry and NGS, plus presenting results at lab meetings and conferences and supervising Master's students. English language required.