Postdoc: Microbiome & Bacterial Cell Wall Research

Biopractify; Paris; Hybride; EUR 42 000 - 56 000; Plein temps

Avantages offerts par ce poste

International collaboration

ANR-funded project

Access to institute facilities

Résumé du poste

Institut Pasteur in Paris invites applications for an ANR-funded postdoctoral fellowship in the Biology and Genetics of the Bacterial Cell Wall Unit. The project focuses on how H. pylori releases peptidoglycan fragments and shapes host immune responses.

Research spans microbiology, mass spectrometry, organoid models, gut-on-chip, and in vivo systems with collaboration from TUM and Monash. The successful candidate will work in an interdisciplinary environment, contribute to publications, and

Qualifications

• Strong background in microbiology.
• Experience or strong expertise in organoid research.
• Interest in microbiome, bacterial cell-wall biology, and host–microbe interactions.
• Experience with LC-MS/MS or mass spectrometry is an advantage.
• Experience with animal models is an advantage.
• Strong interest in studying how bacterial molecules shape host immune responses.
• Ability to work effectively in an interdisciplinary and collaborative research environment.

Responsabilités

• Study how Helicobacter pylori interacts with the host and contributes to immune-system regulation through the release of peptidoglycan fragments.
• Investigate mechanisms involved in release and processing of bacterial peptidoglycan fragments and their effects on host responses.
• Apply mass spectrometry and LC-MS/MS approaches to characterize bacterial cell-wall-derived molecules.
• Use organoid systems to investigate host–microbe interactions and understand how bacterial molecules influence host biology.
• Work with gut-on-chip platforms and in vitro models to study bacterial–host interactions.
• Use animal models to investigate the biological effects and mechanisms of bacterial peptidoglycan fragments in vivo.
• Apply confocal microscopy and cellular imaging approaches to study bacterial interactions and immune-related processes.

Connaissances

Microbiology

Organoid research

Microbiome

Mass spectrometry

LC-MS/MS

Host–microbe interactions

Outils

LC-MS/MS

Description du poste

Institut Pasteur in Paris invites applications for an ANR-funded postdoctoral fellowship in the Biology and Genetics of the Bacterial Cell Wall Unit. The project focuses on how H. pylori releases peptidoglycan fragments and shapes host immune responses.

Research spans microbiology, mass spectrometry, organoid models, gut-on-chip, and in vivo systems with collaboration from TUM and Monash. The successful candidate will work in an interdisciplinary environment, contribute to publications, and