Postdoc in Zebrafish Development & Single-Cell Genomics

EURAXESS Ireland; Paris; Hybride; EUR 42 000 - 54 000; Plein temps

Résumé du poste

CNRS – Institut de Biologie Paris-Seine (IBPS) in Paris invites applications for a postdoctoral researcher to explore molecular mechanisms of olfactory orifice formation in zebrafish. The project targets skin cell remodelling above the olfactory placode and signals between placodal cells and skin epithelium.

The role integrates developmental biology, molecular biology, single-cell genomics and live imaging, with collaboration across sectors and potential publications.

Qualifications

• PhD in developmental biology, cell biology, molecular biology, genetics or a related field.
• Strong experience in transcriptomics and bioinformatic analysis, preferably single-cell RNA sequencing.
• Interest in developmental biology, epithelial remodelling and tissue morphogenesis.
• Experience with zebrafish, FACS, molecular biology, genetics, imaging or quantitative image analysis would be an advantage, but is not required.

Responsabilités

• Characterise the molecular profiles of remodelled skin cells and compare them with neighbouring skin cells using FACS and single-cell transcriptomics (Smart-seq3).
• Identify and validate candidate molecular regulators of epithelial remodelling and skin–placode interactions using molecular, imaging and genetic approaches.
• Characterise placodal cell populations and investigate their potential molecular signals involved in communication with the skin epithelium.
• Analyse the consequences of candidate gene perturbations using zebrafish genetics, live imaging and quantitative image analysis.
• Integrate molecular, transcriptomic and imaging data and contribute to publications and scientific presentations.

Connaissances

Transcriptomics

Bioinformatics

Single-cell RNA-seq

Developmental biology

Epithelial remodelling

Zebrafish

FACS

Imaging

Formation

PhD in life sciences

Description du poste

CNRS – Institut de Biologie Paris-Seine (IBPS) in Paris invites applications for a postdoctoral researcher to explore molecular mechanisms of olfactory orifice formation in zebrafish. The project targets skin cell remodelling above the olfactory placode and signals between placodal cells and skin epithelium.

The role integrates developmental biology, molecular biology, single-cell genomics and live imaging, with collaboration across sectors and potential publications.