PhD Position: Retina Digital Twin & Systems Biology

CNRS - National Center for Scientific Research; France; On-site; EUR 20,000 - 27,000; Full time

Job summary

CNRS in Toulouse invites applications for a PhD position in the Systems Biology group of the Centre for Integrative Biology (CBI). The project aims to build a multi-scale predictive digital twin of the retina affected by age-related macular degeneration (AMD) by converting molecular maps into Boolean models and ABMs, integrated with omics data.

The successful candidate will work on in silico predictions, compare with in vitro data, and contribute to a therapeutic reorientation strategy under the

Qualifications

• Master's degree in bioinformatics, computational or systems biology or related field.
• Programming experience in Python or R; knowledge of network biology or omics analysis.
• Excellent command of English, good presentation skills.

Responsibilities

• Develop large-scale molecular interaction maps and convert to executable Boolean models.
• Integrate models into an ABM to create a digital twin of the retina affected by AMD.
• Collaborate within the MSCA PANDORA network and validate predictions experimentally.

Skills

Programming

Bioinformatics

English

Quantitative skills

Independent work

Education

Master's in bioinformatics

Tools

Python

R

Boolean modelling

Agent‑based modelling

Job description

CNRS in Toulouse invites applications for a PhD position in the Systems Biology group of the Centre for Integrative Biology (CBI). The project aims to build a multi-scale predictive digital twin of the retina affected by age-related macular degeneration (AMD) by converting molecular maps into Boolean models and ABMs, integrated with omics data.

The successful candidate will work on in silico predictions, compare with in vitro data, and contribute to a therapeutic reorientation strategy under the