Enzymology Senior Scientist

Sanofi; Vitry-sur-Seine; Sur place; EUR 60 000 - 80 000; Plein temps

Résumé du poste

Une entreprise pharmaceutique internationale recherche un Enzymology Senior Scientist à Vitry-sur-Seine. Le candidat idéal est titulaire d'un PhD et possède une expérience en biochimie et biologie moléculaire. Ce rôle implique la découverte et le développement d'enzymes pour des processus biocatalytiques. Rejoignez une équipe innovante au sein d'un environnement dynamique tout en bénéficiant d'une rémunération et de nombreux avantages.

Prestations

Programmes de santé et de bien-être

Congés parentaux de 14 semaines

Opportunités de développement de carrière

Qualifications

• Connaissance de l'utilisation des enzymes en biocatalyse pour produire des intermédiaires API.
• Expérience en expression protéique.
• Maîtrise du français et anglais.

Responsabilités

• Établir la stratégie pour la découverte et l'optimisation des enzymes.
• Planifier et exécuter les expériences en laboratoire.
• Écrire et documenter les protocoles en anglais.

Connaissances

Biologie moléculaire

Microbiologie

Biochimie

Utilisation des enzymes en biocatalyse

Communication

Formation

PhD en biocatalyse, biochimie, biotechnologie ou biologie moléculaire

Description du poste

Le contenu du poste est libellé en anglais car il nécessite de nombreuses interactions avec nos filiales à l’international, l'anglais étant la langue de travail.

This job offer is accessible to all, regardless of gender.

Job title : Enzymology Senior Scientist

• Location: Vitry-sur-Seine, France

About the job

The mission of the CMC Synthetics-Process Chemistry Organization is to deliver robust, innovative, and eco-designed synthetic routes and processes for Sanofi’s medicines in the most efficient, sustainable, and cost-effective way. Your role will be to discover and develop enzyme to be implemented in the biocatalytic processes.

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. Join our state-of-the-art Enzyme Biology team as an Enzymology Senior Scientist, and you’ll contribute to developing new innovative and eco-designed synthetic processes for Sanofi components and products, while enjoying numerous opportunities to broaden your experience and hone your skills.

Main responsibilities:

• To establish the strategy for the discovery, screening and optimization of enzymes for each project, within timelines and budget
• To take part of the global development of the strains considering the requirements of the analytical lab, the HT screening, the purification, after discussion with the concerned lab
• To plan, coordinate, and/or execute the lab experiments, including the use of robotics tools
• To develop the new molecular biology and biochemistry methods
• To realize bibliographic and technologic watch related to the topics ongoing in order to identify new technologies and techniques of interest for delivering best in class results
• To analyze, interpret and present the progress and the results in a multidisciplinary and international environment
• To write the electronic lab book and document protocols required for the activity, as well as descriptions of analytical methods and chemical protocols in English
• To manage scientifically collaborators according to projects requirements, and to take part to the lab organization (maintenance, lab supply, HSE)

About you

Experience :

• Molecular biology, microbiology and biochemistry knowledge are required
• Experience in protein expression and in the use of enzyme in biocatalysis to produce API intermediates
• Knowledge of microbiology and bacterial fermentation
• Knowledge of in silico methods for enzyme optimization
• Knowledge of Machine Learning/Artificial intelligent algorithms is a plus

Soft and technical skills :

• Good communication skills and ability to work cross-functionally. Provide clear and structured explanations of its studies to other local functions and to other cross site functional groups
• Rigorous and organized, show initiative, proactivity and curiosity, manage priorities
• Molecular biology technics required for the development of enzyme optimization
• Interest in artificial intelligence and in silico modelling would be a plus
• Ability to build and conduct research scientific program related to project of interest and to guide others in these areas
• Ability to manage the technical monitoring of CRO/CDMO subcontracting (technical discussion for the outsourcing of enzyme optimization)

Education :

• PhD in biocatalysis, biochemistry, biotechnology, molecular biology or any related topics or Master degree with proven experience in any of cited topics

Languages :

• French
• English

Why choose us?

• Bring the miracles of science to life alongside a supportive, future-focused team
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave
• Play an instrumental part in creating best practice within our manufacturing facility

Pursue Progress . Discover Extraordinary .

Progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. You can be one of those people. Chasing change, embracing new ideas and exploring all the opportunities we have to offer. Let’s pursue progress. And let’s discover extraordinary together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com !

#LI-FRA

#LI-Onsite

Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!