VAC_54_2026 - POSTDOCTORAL RESEARCHER (Chromatin biology laboratory)

Carrerasresearch; Badalona; Hybrid; EUR 36,000 - 48,000; Full time

Benefits offered by this job

3-year contract with extension

Full-time 39h/w

Competitive salary

Multidisciplinary project

Barcelona metro area

Job summary

The Josep Carreras Leukaemia Research Institute (IJC) solicits applications for a Postdoctoral Researcher in the Chromatin Biology Laboratory led by Dr. Alejandro Vaquero.

The project studies SIRT7/PAX5 interplay in B-cell differentiation and B-ALL using mouse models, proteomics, and genomics to understand genome regulation under stress. The successful candidate will join a multidisciplinary team in Barcelona, with a 3-year contract, highly competitive salary, and access to cutting-edge

Qualifications

• PhD in Biology, Biomedicine, Medicine, or a related discipline.
• Strong interest in cancer biology, especially stress response, hematological malignancies, and immune regulation.
• Demonstrated experience with mouse models (essential), preferably in leukemia and/or sirtuin biology.
• Expertise in molecular and cellular biology techniques, including protein biochemistry, immunofluorescence, flow cytometry (FACS), and experience with proteomic and genomic approaches (essential).
• Previous experience in stress response pathways and/or sirtuin biology is highly desirable.
• Excellent communication, organizational, and teamwork skills.
• Excellent written and spoken English.

Responsibilities

• Explore molecular and epigenetic mechanisms controlling SIRT7/PAX5 interplay in B-cell differentiation and B-ALL.
• Use multidisciplinary approaches combining molecular biology, genomics, proteomics in mouse and patient-derived leukemia models.
• Collaborate with clinical and pre-clinical B-ALL researchers and drug discovery teams.

Skills

Mouse models

Molecular biology

Flow cytometry (FACS)

Proteomics & Genomics

English communication

Education

PhD in Biology/ Biomedicine/ Medicine

Tools

Proteomics

Genomics

Immunofluorescence

Bioinformatics

Job description

Postdoctoral Researcher – Chromatin Biology Laboratory

The Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive cancer research center dedicated to the study of leukaemia and other hematologic malignancies. We are seeking a Postdoctoral Researcher for the Chromatin Biology Laboratory led by Dr. Alejandro Vaquero.

RESEARCH DESCRIPTION

The Chromatin Biology Laboratory focuses on the role of the Sirtuin family of enzymes in regulating genome stability and epigenetics under stress conditions, and their impact on cancer, senescence, and aging.

MAIN RESPONSIBILITIES

The successful candidate will explore the molecular and epigenetic mechanisms controlling the SIRT7/PAX5 interplay in B-cell differentiation and B‑Acute Lymphoblastic Leukemia (B‑ALL). The project utilizes a multidisciplinary approach, combining molecular and cellular biology techniques with genomics, proteomics, and metabolomics in mouse models and patient‑derived leukemia models.

QUALIFICATIONS

• PhD in Biology, Biomedicine, Medicine, or a related discipline.
• Strong interest in cancer biology, especially the mechanisms underlying stress response, hematological malignancies, and immune regulation.
• Demonstrated experience with mouse models (essential), preferably in leukemia and/or sirtuin biology.
• Expertise in molecular and cellular biology techniques, including protein biochemistry, immunofluorescence, flow cytometry (FACS), and experience with proteomic and genomic approaches (essential).
• Previous experience in stress response pathways and/or sirtuin biology is highly desirable.
• Excellent communication, organizational, and teamwork skills.
• Excellent written and spoken English.

BENEFITS

• 3‑year full‑time postdoctoral contract with potential one‑year extension following a positive evaluation.
• Full‑time contract (39 hours/week).
• Highly competitive salary.
• Exciting multidisciplinary research project with strong potential to advance B-cell acute lymphoblastic leukemia treatment.
• Collaboration with world leaders in clinical and pre‑clinical B‑ALL research and drug discovery.
• Opportunity to work in the outstanding multidisciplinary environment of the IJC.
• Stimulation of the Barcelona metropolitan area environment.

DEADLINE

Please submit your application by July 22nd, 2026.

The IJC is an equal‑opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, or other legally protected characteristics.