Senior AI Scientist, Clinical Development

AstraZeneca plc; Spain; On-site; EUR 90,000 - 130,000; Full time

Job summary

AstraZeneca plc in Barcelona, Spain, is seeking a Senior Scientist to lead hands‑on research and delivery of advanced AI models for clinical‑development decisions and workflows. This in‑office role requires a minimum of three days on‑site per week with no remote option.

You will work at the intersection of frontier AI, clinical trial methodology, and biomedical science, delivering robust AI-enabled solutions, evaluating models, and guiding strategy.

Qualifications

• Hold an MSc or PhD in Computer Science, Machine Learning, Biostatistics, Biomedical Informatics, Computational Biology, or a closely related quantitative field, or have a BSc with substantial equivalent experience.
• Have independently delivered a meaningful AI or ML research project, workstream, model, evaluation, or software capability from initial question through a clear and reproducible result.
• Have a record of strong research or technical contributions, such as peer-reviewed work, validated models, reusable software, datasets, benchmarks, patents, or deployed capabilities.
• Bring expertise in relevant research topics, such as unsupervised learning, dimensionality reduction, causal inference, survival or longitudinal analysis, Bayesian modeling, multimodal learning, domain adaptation, model interpretability.

Responsibilities

• Own the end-to-end scientific and technical delivery of one or more clinical AI workstreams, from problem definition and data assessment through prototyping, validation, translation, and iteration.
• Adapt and apply emerging AI methods to clinical-development problems, investigate failure modes, and make clear recommendations based on the evidence
• Build and evaluate agentic AI systems for clinical-development use cases, including retrieval, tool use, code execution, memory, multi-step workflows, and human oversight.
• Write high-quality Python and build reproducible research workflows using modern ML frameworks, version control, testing, and cloud or high-performance computing environments.
• Act as a senior scientific and technical partner across the organization, influencing clinical strategy, evaluation approaches, platform capabilities, and investment decisions.
• Share your work through peer-reviewed publications, reusable tools, patents, scientific collaborations, and conference presentations where appropriate.
• Build the research culture of the team through scientific review, constructive challenge, and mentorship of scientists and engineers.
• Represent AstraZeneca with external partners, scientific consortia, regulators, and the research community

Skills

Python

PyTorch

JAX

TensorFlow

Unsupervised learning

Dimensionality reduction

Causal inference

Survival analysis

Longitudinal analysis

Bayesian modeling

Multimodal learning

Domain adaptation

Model interpretability

Education

MSc or PhD in Computer Science, Machine Learning, Biostatistics, Biomedical Informatics, Computational Biology, or related field

Tools

PyTorch

JAX

TensorFlow

Cloud computing

Job description

AstraZeneca plc in Barcelona, Spain, is seeking a Senior Scientist to lead hands‑on research and delivery of advanced AI models for clinical‑development decisions and workflows. This in‑office role requires a minimum of three days on‑site per week with no remote option.

You will work at the intersection of frontier AI, clinical trial methodology, and biomedical science, delivering robust AI-enabled solutions, evaluating models, and guiding strategy.