Student Research Assistant (HiWi) in Cancer Immunotherapy – Department of Medicine 2, Hematolog[...]

Universitätsklinikum Frankfurt; Frankfurt; Vor Ort; EUR 30.000 - 45.000; Vollzeit

Zusammenfassung

Join a leading cancer research lab at Goethe University Hospital Frankfurt, focusing on cutting-edge cancer therapies and molecular biology. You'll support laboratory operations and engage in impactful research aimed at advancing CAR T cell therapy. This position offers a unique opportunity for hands-on experience in an international environment with flexible hours tailored to your studies.

Leistungen

Collective labour agreement (TV GU)

International working environment

Contract for at least 1 year

Flexible working hours

Scientific education opportunities

Campus amenities (Mensa, Cafés)

Qualifikationen

• Enrolled in a university program (bachelor or master) in biology or related discipline.
• High motivation for experimental lab work.
• Experiences in cell and molecular biology are advantageous.

Aufgaben

• Support day-to-day wet-lab operations focused on molecular cloning and AAV vector production.
• Construct plasmids, perform transfections, and maintain cell cultures.
• Produce and titer viral vectors while conducting assays.

Kenntnisse

Experimental lab work

Cell and molecular biology

Biochemical lab techniques

Team collaboration

Responsibility

Proactivity

Fluent in English

Ausbildung

Bachelor or Master in Biology, Biochemistry or related discipline

Tools

MS-Office (Word, Excel)

Jobbeschreibung

...you're in the middle of it

TheDepartment of Medicine 2, Hematology/ Oncologyat theGoethe UniversityHospital Frankfurtoffers the entire spectrum of diagnostics and therapy of malignant diseases as well as a research program focusing on several cancer entities. The research laboratory of Professor Thomas Oellerich is part of the Frankfurt Cancer Institute and focuses on oncogenic signaling and therapy resistance mechanisms in lymphoma and acute myeloid leukemia.

The lab is furthermore funded by the German Cancer Consortium (DKTK), which was founded in 2012 as one of the six German Centers of Excellence for Health Research (DZG). DKTK aims at bringing promising results from cancer research faster into clinical development and patient care. In the DKTK more than 20 academic research institutions and university hospitals at seven partner sites cooperate with each other and the German Cancer Research Center (DKFZ) in Heidelberg as the core center. (https://dktk.dkfz.de/standorte/frankfurt-mainz)

Your Role:

You will support day-to-day wet-lab operations, with a focus on molecular cloning, production of AAV vectors, and maintenance of mammalian cell lines.

The project focuses on developing targeted AAV vectors to enhance the efficacy of CAR T cell therapy against aggressive lymphomas. By integrating the latest advances in vector engineering, immunotherapy, and gene delivery, the research aims to significantly improve therapeutic outcomes. This work combines cutting-edge technologies to push the boundaries of next-generation cancer treatments.

• Construct plasmids (restriction/ligation, PCR, bacterial transformation)
• Perform transfections (chemical/electroporation) and basic viability or reporter assays
• Maintain, passage and cryopreserve adherent and suspension cell cultures under sterile conditions
• Produce and titer viral vectors (e.g., lentivirus, AAV
• Transduction & FACS analysis with the vector stocks

... your skills are what we're looking for

• Enrolled in a university program (bachelor or master) in biology, biochemistry or a related discipline
• Enthusiasm and fascination for biomedical research, oncology, cell and molecular biology
• High motivation for experimental lab work
• Experiences in cell and molecular biology as well as biochemical lab techniques might be of advantage
• Ability to work in a team, sense of responsibility and proactivity
• Basic knowledge in MS-Office (Word, Excel)
• Fluent in English
• Due to legal regulations, valid proof of measles immunity / measles vaccination is required

... you'll be offered a lot

• Collective labour agreement TV GU
• International and cosmopolitan working environment
• Contract for at least 1 year
• Flexible working hours in line with your studies
• Scientific education including the management of scientific literature, a bi-weekly journal club, good scientific presentation and publication practice
• Uniklinik-Campus, Mensa, Cafés
• Insights: Instagram, YouTube, LinkedIn
• FAQ´s for new employees

It's time to join our team!

Contact: Dr. Niklas Dienstbier (Team Lead - Mechanistic Lymphoma Research)
Phone or Email: 069-6301-84001 or [e-mail]
Application Deadline: 10.07.2025

We welcome applications from candidates of all genders. Women are currently underrepresented in these positions at Universitätsmedizin Frankfurt. Therefore, applications from women are especially encouraged. Applicants with severe disabilities will be given preferential consideration in cases of equal personal and professional qualifications.