Senior Scientist in Translational Immunology (m/f/d)

Fraunhofer-Gesellschaft; Berlin; Vor Ort; EUR 45.000 - 65.000; Teilzeit

Zusammenfassung

Das Fraunhofer-Institut für translationale Medizin und Pharmakologie ITMP in Berlin sucht einen Postdoktoranden für die Entwicklung neuer Behandlungsstrategien bei rheumatischen Erkrankungen. Mit umfangreichen Erfahrung in der translationalen Forschung und Immunologie werden Sie in einem innovativen Team arbeiten, um die Mechanismen zwischen zellulärer Therapie und Immunantwort zu untersuchen.

Qualifikationen

• Promotion in Biologie/Naturwissenschaften mit Erfahrung in lymphozytischer Immunologie.
• Erfahrung in translationaler Forschung und komplexer bioinformatischer Datenanalyse.
• Exzellente Kommunikationsfähigkeiten in Deutsch und Englisch.

Aufgaben

• Entwurf von Experimenten, Erstellung von SOPs und Kostenkalkulation.
• Koordination der Probenentnahme zwischen Klinik und Labor.
• Durchführung fortgeschrittener Analysetechniken und Datenanalyse.

Kenntnisse

Kommunikationsfähigkeiten

Teamfähigkeit

Kreativität

Flexibilität

Ausbildung

Promotion in Biologie/Naturwissenschaften

Tools

R

Python

Jobbeschreibung

The Fraunhofer Institute for translational medicine and pharmacology ITMP, location Berlin Mitte, focuses on the development of new and personalised treatment strategies for patients with rheumatic diseases. This new Fraunhofer location, being developed in cooperation with the Charité- Universitätmedizin Berlin, is looking for a postdoctoral researcher with experience in translational immunology with immediate effect.

What you will do

Our clinic conducts a number of trials, including Investigator-Initiated Trials (IITs) in order to develop novel treatment modalities for rheumatic diseases. This includes the use of CAR T cells and therapeutic antibodies to reset the immune system. It will be your task to investigate the effect on the immune system during and after treatment in order to gain insights into the mechanism, efficacy and durability of the approach. For this, you will perform a number of advanced approaches including spectral flow cytometry, single cell sequencing and spatial analysis of tissue biopsies. You will be responsible for:

• experimental design, writing of SOPs and costing of the required scientific analyses
• the coordination of sample collection and processing between the clinic and the technicians in the lab
• Performance of advanced analysis techniques, including flow cytometry, cell sorting, single cell sequencing, high-parameter biomarker analysis, imaging techniques.
• data analysis

In addition to your work on the trials, you will be part of the academic research lab and assist basic research, including the guidance of PhD student projects.

What you bring to the table

• A PhD in the field of biology/natural sciences with advanced experience in lymphocyte immunology
• Experience with translational research
• Experience with complex bioinformatic data analysis including the use of R and Python.
• Excellent communication skills and proficiency in both German and English
• Motivation and an ability to work in a team
• Adaptability, flexibility and creativity

What you can expect

The weekly working time is 39 hours. This position is initially limited until 31 December 2025 and is also available on a part-time basis. We value and promote the diversity of our employees' skills and therefore welcome all applications - regardless of age, gender, nationality, ethnic and social origin, religion, ideology, disability, sexual orientation and identity. Severely disabled persons are given preference in the event of equal suitability. Appointment, remuneration and social security benefits based on the public-sector collective wage agreement (TVöD).

With its focus on developing key technologies that are vital for the future and enabling the commercial utilization of this work by business and industry, Fraunhofer plays a central role in the innovation process. As a pioneer and catalyst for groundbreaking developments and scientific excellence, Fraunhofer helps shape society now and in the future.

Interested? Apply online now. We look forward to getting to know you!

Fraunhofer Institute for Translational Medicine and Pharmacology ITMP

www.itmp.fraunhofer.de

Requisition Number: 80074