Senior Scientist - Cellular Functional Assays and Organoids (m/f/d)

WuXi AppTec Group; München; Hybrid; EUR 70,000 - 110,000; Full time

Job summary

WuXi AppTec Group in Munich, Germany seeks an experienced Senior Scientist to lead our cellular assay team. You will design, execute, and interpret cellular functional assays to validate activity of small molecules and other modalities, contributing to drug discovery projects for clients.

You will collaborate across departments, drive innovative assays, and mentor junior scientists. The role requires a PhD and strong hands-on experience in mammalian cell culture and assay development, with

Qualifications

• PhD in Biology or related field required.
• 2+ years hands-on mammalian cell culture experience.
• Experience in designing cellular assays to assess small molecule activity.
• English communication is essential; German a plus.

Responsibilities

• Design and conduct cellular functional assays for hit characterization, high-throughput screening, and compound profiling.
• Lead development of state-of-the-art assays for cellular profiling and characterization of small molecule activity.
• Optimize and miniaturize robust screening assays to enhance efficiency and reliability.
• Collaborate with cross-functional teams to ensure successful delivery of client projects.

Skills

PhD in Biology

Cell culture

Cellular assays

English communication

Education

PhD in Biology

Job description

Overview

We are seeking an experienced Senior Scientist to join and shape our cellular assay team based in Munich, Germany. In this key role, you will be responsible for designing, executing, and interpreting cellular functional assays to validate the activity of small molecules and other therapeutic modalities. Your expertise in cutting-edge methodologies will be crucial in delivering high-quality data, which supports the success of our client projects. Collaborating closely with various departments at Crelux will be essential to drive innovative solutions and accelerate drug discovery programs.

Responsibilities

• Design and conduct cellular functional assays for hit characterization, high-throughput screening, and compound profiling
• Lead the development of state-of-the-art assays, ensuring innovative and high-quality designs for cellular profiling and characterization of small molecule activity
• Optimize and miniaturize robust screening assays to enhance their efficiency and reliability
• Work closely with cross-functional teams to ensure the successful delivery of client projects, contributing to their overall success

Qualifications

• PhD (m/f/d) in Biology, Cell Biology, Molecular Biology, Biochemistry, or a related scientific field
• 2+ years of hands-on experience in mammalian cell culture and developing cellular functional assays for drug development projects
• Expertise in designing advanced cellular assays to assess the activity of small molecules and other modalities (e.g., target engagement, signaling, and reporter assays)
• Experience with 3D models, primary cells, and/or organoids is a plus
• Experience with CRISPR/Cas9 tools is an advantage
• Strong analytical and problem-solving skills, with exceptional attention to detail
• Excellent communication skills in English (German is a plus)
• Self-starter with the ability to work independently, while also thriving in a collaborative, multidisciplinary team environment