Senior Project Manager Hit & Lead Discovery

Proteros Biostructures; München; On-site; EUR 90,000 - 120,000; Full time

Job summary

Proteros Biostructures in Munich, Germany seeks a Senior Project Manager for Hit & Lead Discovery to guide multiple early discovery projects from initiation through delivery. You will be the primary client contact, ensuring clear communication, objective alignment, and high satisfaction while coordinating cross-functional teams across hit finding, lead progression, and data interpretation.

The ideal candidate holds a PhD in a life sciences field (Chemistry, Biology, Pharmacology) or an MSc with

Qualifications

• Track record leading complex discovery projects and teams.
• Experience in CRO/biotech/pharma environments.
• Experience communicating with clients and stakeholders.

Responsibilities

• Act as primary client contact ensuring clear communication and alignment.
• Lead concurrent early discovery projects from initiation to delivery.
• Translate client goals into actionable project plans, timelines, and deliverables.
• Identify risks and implement mitigation strategies.
• Coordinate internal resources to ensure timely project execution.

Skills

Project management

Client management

Communication

Cross-functional collaboration

Risk management

Education

PhD in Chemistry/ Biology/ Pharmacology

MSc in Life Sciences (considered)

Tools

PM software

Job description

Senior Project Manager Hit & Lead Discovery

Proteros Biostructures

Munich, Germany

Your mission

Project Leadership & Client Management

• Serve as the primary point of contact for clients, ensuring clear communication, alignment on objectives, and high client satisfaction;
• Lead multiple concurrent early discovery projects from initiation through delivery;
• Translate client goals into actionable project plans, timelines, and deliverables;
• Proactively identify risks and implement mitigation strategies.

Scientific Oversight

Oversee and guide scientific activities across:

• Hit finding (e.g., protein production, screening, assay development, structure determination, in silico screening);
• Hit-to-lead progression.
• Collaborate with cross-functional scientific teams (e.g., medicinal chemistry, biophysics, computational chemistry, structural biology, biochemistry);
• Ensure scientific rigor, data quality, and strategic alignment with client objectives;
• Interpret and communicate complex scientific data to both technical and non-technical stakeholders.

Resource & Operational Management

• Coordinate internal resources across multiple departments to ensure timely project execution;
• Monitor project progress, budgets, and scope; adjust plans as needed;
• Facilitate internal meetings, track milestones, and ensure accountability;
• Support capacity planning and resource allocation in collaboration with department heads.

Business & Strategic Contribution

• Contribute to proposal preparation, project scoping, and budgeting for new business opportunities;
• Support business development activities by providing scientific and operational insights;
• Identify opportunities for process improvements and operational efficiency within project workflows.

Your profile

• Demonstrated experience in early discovery stages: hit identification through lead optimization;
• PhD in Chemistry, Biology, Pharmacology, or related life sciences field preferred;
• MSc with significant relevant experience may be considered;
• 3–7+ years of experience in drug discovery, ideally within a CRO, biotech, or pharmaceutical environment;
• Proven track record of managing complex, cross-functional scientific projects;
• Experience in client-facing roles strongly preferred;
• Strong understanding of drug discovery workflows and decision-making processes;
• Excellent project management skills (planning, risk management, prioritization);
• Exceptional communication and stakeholder management abilities;
• Ability to manage multiple projects in a dynamic, deadline-driven environment;
• Strong analytical thinking and problem-solving skills;
• Familiarity with project management tools and scientific data systems.