Senior Principal Scientist - Drug Substance Process Chemistry (m/f/d) (m/f/d)

Bayer; Deutschland; Vor Ort; EUR 80.000 - 100.000; Vollzeit

Zusammenfassung

A global pharmaceuticals company is seeking a Senior Principal Scientist in Drug Substance Process Chemistry. The role involves optimizing chemical processes and ensuring safety compliance, while managing projects effectively. The ideal candidate holds a PhD in organic chemistry and is fluent in German and English. This position is located in Wuppertal-Elberfeld, North Rhine Westfalia, Germany. Join us to tackle major challenges in health and sustainability.

Qualifikationen

• Extensive expertise in industrial process chemistry and chemical API development.
• Strong project management skills with stakeholder management experience.
• Excellent knowledge of classical and modern synthetic methods.

Aufgaben

• Develop and optimize assigned chemical processes for improved yield, quality, and cost.
• Contribute to process transfers from laboratories to production sites.
• Evaluate and apply new chemical technologies and methods.

Kenntnisse

Project management

Interpersonal skills

Presentation skills

Fluency in German

Fluency in English

Creativity in problem solving

Ausbildung

PhD in organic chemistry or related discipline

Tools

Modern tools in digital chemistry

Jobbeschreibung

At Bayer we\'re visionaries, driven to solve the world\'s toughest challenges and striving for a world where ,Health for all, Hunger for none\' is no longer a dream, but a real possibility. We\'re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining \'impossible\'. There are so many reasons to join us. If you\'re hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there\'s only one choice.

Senior Principal Scientist - Drug Substance Process Chemistry (m/f/d) (m/f/d)

You will join the Drug Substance Small Molecules (DSSM) team within the CMC&T unit. Our team offers a broad range of expertise across Process Chemistry, Process Industrialization, Process Technologies & Protein Engineering, Launch and Lifecycle Management. We collaborate closely with our partners in Research and Development, CMC and API manufacturing. Our team is responsible for early and late-stage technical development of our synthetics chemical API pipeline, manufacture of drug substance for clinical studies, and transfer of the processes to manufacturing.

In Process Chemistry, we develop phase-appropriate chemical manufacturing processes for clinical API candidates. While meeting supply demands, our focus is to identify optimal processes with regard to robustness, quality, cost, safety and sustainability. To achieve this goal, we leverage state-of-the-art synthesis know-how in combination with automation and data science.

YOUR TASKS AND RESPONSIBILITIES

• You are responsible for the development and optimization of assigned chemical processes generating benefits in yield, quality and cost. The scope includes small molecules as well as synthetic modalities such as protein conjugates or peptides
• You contribute as part of project teams to process transfers from laboratories to the relevant production plant or site (scale up) internally and/or externally
• You ensure competitiveness of production processes by evaluating and applying new and state-of-the-art chemical technologies and methods
• You provide scientific input and guidance to laboratory teams always ensuring compliance with safety regulations
• You develop and maintain comprehensive documentation of experimental procedures, results, and protocols
• You stay up-to-date with the latest advancements in process chemistry and technologies and take ownership for implementing new technologies and methods
• You drive excellence in synthetic chemistry within Drug Substance Small Molecules and across the Bayer-wide chemistry community
• You present findings and progress updates to internal stakeholders and at external conferences and workshops
• You co-shape way of working within Process Chemistry cluster, embracing our Dynamic Shared Ownership operating model

WHO YOU ARE

• You hold a PhD in organic chemistry or related discipline and have extensive expertise in industrial process chemistry and chemical API development
• You have strong project management skills including generation of vision and outcomes, tracking of progress and stakeholder management
• You have strong interpersonal and influencing skills, with demonstrated ability to build trustful relationships and motivate team members
• You have excellent presentation and communication skills, including the ability to communicate across multiple levels within and outside the organization
• Excellent knowledge of classical and modern synthetic methods, knowledge of modern tools in digital chemistry and automation is a plus
• Demonstrated high level of creativity and independence in solving complex scientific problems by designing, executing, and evaluating solution-oriented chemical experiments
• You are fluent in German and English, both verbal and written

YOUR APPLICATION

This is your opportunity to tackle the world\'s biggest challenges with us: Maintaining our health, feeding growing populations and slowing the rate of climate change. You have a voice, ideas and perspectives and we want to hear them. Because our success begins with you. Be part of something big. Be Bayer.

Bayer welcomes applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.

Location: Germany : North Rhine Westfalia : Wuppertal-Elberfeld

Division: Pharmaceuticals

Reference Code: 854162