Senior Bioinformatician (Location: Berlin/Valencia/Belgrade/Remote)

CENTOGENE GmbH; Deutschland; Remote; EUR 70.000 - 90.000; Vollzeit

Zusammenfassung

A leading bioinformatics company is seeking a Senior Bioinformatician to support the development of a cloud-based bioinformatics platform. In this role, you will design scalable data analysis pipelines, enhance genomic data processes, and contribute to algorithm optimization. The ideal candidate holds a Ph.D. and has extensive experience in bioinformatics software development and cloud environments. Strong skills in Python and data analysis are required.

Qualifikationen

• Ph.D. or Master's in a related field with extensive experience.
• Demonstrated experience in bioinformatics software development.
• Hands-on with cloud-based environments.

Aufgaben

• Lead design and implementation of bioinformatics pipelines.
• Enhance genomic bioinformatics data and pipelines.
• Collaborate with Dry lab teams for tool development.

Kenntnisse

Expertise in Python

NGS data analysis

Collaboration skills

Problem-solving skills

Organizational skills

Ausbildung

Ph.D. in Bioinformatics or related field with 7+ years experience

Master's degree with 9+ years experience

Tools

AWS (Batch, Lambda, Step Functions)

MySQL

Version control (Git)

Jobbeschreibung

Deine Aufgaben

We are seeking a highly skilled and experienced Senior Bioinformatician to join our Bioinformatics team, supporting the development of CentoDX, our advanced cloud-based bioinformatics platform. In this role, you will lead the design and implementation of robust, scalable data analysis pipelines and actively contribute to algorithm optimization, data integration, and automation across our clinical diagnostics workflows.

• Design, develop, and maintain bioinformatics analysis pipelines for sequence alignment, variant calling, annotation, and other data processing pipelines.
• Lead the upgrade and enhancement of genomic bioinformatic data and pipelines, ensuring compatibility and accuracy
• Maintain and enhance internal MySQL databases and ensure regular updates from external data sources (e.g., gnomAD, ClinVar, HGMD, RefSeq)
• Oversee the continual update and validation of gene, transcript, and functional annotation pipelines in line with best practices
• Drive development and refinement of bioinformatics algorithms to improve diagnostic accuracy and data interpretation
• Lead the automation of tertiary analysis pipelines, ensuring scalability, reproducibility, and high-throughput performance
• Collaborate closely with the Dry lab teams to translate scientific requirements into production-ready tools and support clinical decision-making
• Identify and implement strategies for continuous improvement in data workflows, system performance, and data quality

Dein Profil

• Ph.D. in Bioinformatics, Computational Biology, Computer Science, or related field with 7+ years of experience; or Master's degree with 9+ years of relevant industry experience
• Proven expertise in Python for bioinformatics software and pipeline development
• Hands-on experience in NGS data analysis ( e.g., WES/WGS, RNA-seq, variant interpretation tools)
• Familiarity with public and proprietary bioinformatics resources (e.g., UCSC Genome Browser, TCGA, Ensembl, ClinVar, gnomAD)
• Strong understanding of genomic data standards, formats (VCF, BED, GTF), and bioinformatics best practices
• Demonstrated experience working in cloud-based environments (AWS preferred) with tools like AWS Batch, Lambda, or Step Functions
• Experience with relational databases, particularly MySQL, for data management and integration
• Solid understanding of software engineering principles, version control (Git), and reproducible research workflows
• Strong organizational skills with the ability to prioritize tasks, meet deadlines, and align with company objectives
• Excellent problem-solving skills and ability to work collaboratively in cross-functional teams