Scientist | MS Biomarker Research / Proteomics

Boehringer Ingelheim; Biberach an der Riß; Vor Ort; EUR 70.000 - 100.000; Vollzeit

Zusammenfassung

Boehringer Ingelheim is seeking a highly motivated Scientist to join the Mass Spectrometry based Biomarker team within the Drug Discovery Sciences (DDS) department in Germany. You will advance proteomics methods and contribute to first-in-class biomarker discovery and translational sciences while collaborating across project teams.

Based in our Biberach site, you will design and execute DIA proteomics experiments, operate LC-MS systems, analyze data, educate colleagues, and help shape discovery

Qualifikationen

• Master's or PhD in a relevant discipline with hands-on DIA experience
• Experience with proteomics workflows and sample prep for LC-MS analyses
• Solid understanding of biochemistry, molecular mechanisms, and pharmacology in drug discovery

Aufgaben

• Review requests for biomarker discovery and quantitation; align with project teams
• Design, execute, and analyze proteomics experiments including biomarker discovery and PTM identification
• Use omics platforms for translational topics and MoA elucidation in collaboration with R&D partners
• Perform practical lab work generating and analyzing proteomics samples and operating LC-MS systems
• Educate and train colleagues in proteomic analysis and develop expertise in drug development

Kenntnisse

Proteomics

Mass spectrometry

Data analysis

Experimental design

Ausbildung

Master's degree in mass spectrometry-based proteomics

PhD in related field

Tools

Orbitrap

QTOF

LC-MS

Jobbeschreibung

We are seeking a highly motivated Scientist to join our Mass Spectrometry based Biomarker team within the Drug Discovery Sciences (DDS) department in Germany. You'll work at the cutting edge of drug discovery - shaping breakthrough therapies and making an immediate impact. In this role, you will represent your scientific discipline in cross-functional teams, advance cutting-edge methods in proteomics, mass spectrometry, and molecular sciences. You will help shape "first-in-class" opportunities across our discovery portfolio and contribute to a culture of scientific excellence. If you are a highly motivated scientist with proteomics background, a passion for biomarker research and translational sciences, we invite you to apply for this opportunity. Join our team and contribute to the development of innovative therapies that improve patients' lives.

Discover our Biberach site: xplorebiberach.com

Tasks & responsibilities

• In your new role, you will scientifically review requests for biomarker discovery & quantitation, will align the purpose and path-forward with our partners in project teams
• Furthermore, you will lead the design, execution, and analysis of proteomics experiments, including Biomarker discovery, targeted quantification, PTM identification, or interactome determination
• You will be using Omics-platforms for translational topics, NTC confirmation, functional validation and MoA elucidation in alignment with our research & development partners
• Moreover, a major aspect of this role involves practical lab work, including generating and analyzing proteomics samples, as well as operating and maintaining various LC-MS systems
• With your high interest in innovative approaches, you will challenge the 'status quo' and further advance the scientific and proteomics workflows
• In addition, you will educate and train Boehringer Ingelheim colleagues in proteomic analysis and continue to develop scientific and drug development expertise

Requirements

• Completed Master's degree /Phd in mass spectrometry-based proteomics, biochemistry, pharmacology, or a related scientific discipline with several years of relevant hands-on experience with data-independent acquisition (DIA) workflows on a Thermo orbitrap Astral mass spectrometer. First insights into drug discovery programs within the pharma industry is beneficial
• Experience with state-of-the-art proteomics workflows as well as experience in sample preparation from cells and tissues for LC-MS analyses. First experience with characterizing disease-relevant animal models for translational aspects is a plus
• Solid understanding of biochemistry, molecular mechanisms, and pharmacology relevant to drug discovery as well as conceptual understanding of biomarkers in drug discovery and development paired with first experience in this field
• Expertise in operating cutting-edge mass spectrometry platforms (Orbitrap, QTOF, etc.) and expert understanding of respective analysis software
• Analytical mindset, with a keen interest in advancing proteomic methodologies and the ability to work independently and collaboratively in an interdisciplinary research environment
• Critical and creative thinking, self‑motivated to innovate
• Excellent data analysis and data management skills, as well as presentation skills
• Fluent written and spoken English and German (a plus)

Start date: asap

As part of our commitment to transparency and fairness, salary information will be shared during the recruitment process. We also offer a comprehensive benefits and wellbeing package.

Applications from persons with severe disabilities are warmly welcomed. In cases of equal qualifications, such applicants will be given preferential consideration in the selection process.

Our Company

Boehringer Ingelheim is a biopharmaceutical company active in both human and animal health. As one of the industry's top investors in research and development, the company focuses on developing innovative therapies that can improve and extend lives in areas of high unmet medical need. Independent since its foundation in 1885, Boehringer takes a long‑term perspective, embedding sustainability along the entire value chain. Our approximately 54,300 employees serve over 130 markets to build a healthier and more sustainable tomorrow. Learn more at www.boehringer-ingelheim.com.

Why Boehringer Ingelheim?

With us, you can develop your own path in a company with a culture that knows our differences are our strengths - and break new ground in the drive to make millions of lives better.

Here, your development is our priority. Supporting you to build a career as part of a workplace that is independent, authentic and bold, while tackling challenging work in a respectful and friendly environment where everyone is valued and welcomed.

Alongside, you have access to programs and groups that ensure your health and wellbeing are looked after - as we make major investments to drive global accessibility to healthcare. By being part of a team that is constantly innovating, you'll be helping to transform lives for generations.

Want to learn more? Visit https://www.boehringer-ingelheim.com