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A leading biotechnology company seeks a bioanalytical scientist for its Molecular Biochemistry department in Berlin. The role involves advanced mass spectrometry techniques to evaluate protein pharmaceuticals, requiring strong qualifications in the relevant sciences and a passion for research and development.
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Octapharma Biopharmaceuticals GmbH a subsidiary of the Octapharma group founded in 1997 is a successful and expanding biotech company in Heidelberg. Our core business is the development of recombinant proteins produced in human cell lines for therapeutic use in humans. We strive for effective treatments with an improved tolerability and convenience for our patients.
The Molecular Biochemistry department, based in Berlin, Germany, develops technologies to study the structure and function of plasma-derived and recombinant proteins. It has developed new ways to decipher the relationships between different plasma proteins and their influence on the immune system. The unit's cutting-edge methods support product development, regulatory compliance as well as life-cycle management.
A position is available for a bioanalytical scientist to join the mass spectrometry research team at Octapharma’s Molecular Biochemistry department in Berlin. For the evaluation of our protein pharmaceuticals, we use a variety of proteomics approaches ranging from protein identification and quantification to PTM analysis. Methods such as Crosslinking MS for structural analysis and immunopeptidomics for immunogenicity evaluation were recently established to support the drug development. We are looking for a Scientist (m/f/d) passionate about learning and quickly applying new skills to project needs. The full-time position is temporary for 14 months and preferentially starting in September 2025.
• A committed team and a collegial environment
• A challenging, multifaceted and interesting job
• A modern - “state of the art” - working environment
• Flexible working hours, 30 days vacation/year
• Water, coffee and tea for free
• Fresh fruits and vegetables
• Sustainable travel to work: subsidized Germany Job Ticket and Job-Bike leasing
• Corporate Benefits
• Prepare samples for mass spectrometry, run samples and analyze the data
• Contribute to the day-to-day running and operation of the nano-LC-MS instruments
• Independently design and conduct analytical experiments and method development as needed
• Collaborating with and supporting other lab members on research projects
• Data interpretation and documentation of experimental results
• Communication of experimental results to team members
• Participate in regular group meetings, including weekly lab meetings
Required qualifications
• BS/MS/PhD degree in chemistry, biological sciences, biochemistry or related fields
• Demonstrated experience in a variety of MS-based applications for the analysis of proteins/peptides
• Skilled in protein/peptide sample preparation techniques including BCA/Bradford protein quantification, SDS-PAGE, in-gel and solution proteolytic digestion protocols
• Self-starter and able to work independently and as part of a multidisciplinary team
• Strong data organization, analysis, and communication skills
• Ability to multitask
Preferred qualifications
• Experience with nanoElute and timsTOF Pro in hard- and software
• Experience with data analysis software (PEAKS, Spectronaut, Skyline)
• General experience in the field of immunogenicity
• Programming skills in python scripts and/or “R”
Octapharma is one of the largest human protein manufacturers in the world, developing and producing human proteins from human plasma and human cell lines. We employ more than 11,000 people worldwide to support the treatment of patients in 120 countries with products across three therapeutic areas: Immunotherapy, Haematology and Critical Care. With seven R&D sites and five state-of-the-art manufacturing facilities in Austria, France, Germany, and Sweden, Octapharma also operates over 195 plasma donation centres across Europe and the US. With four decades of experience, we are committed to advancing patient care worldwide.