Research Position (PhD candidate)

Universität Bielefeld; Bielefeld; Vor Ort; EUR 16.000 - 25.000; Teilzeit

Zusammenfassung

The Faculty of Chemistry at Universität Bielefeld is seeking a PhD candidate for a research position in Structural Biochemistry, focusing on protein structure-function relationships. This part-time role includes research, teaching responsibilities, and offers a supportive working environment with various professional development opportunities.

Leistungen

Internal and external training opportunities

Health and consulting services

Flexible working conditions

Collegial working environment

Open working atmosphere

Various offers (canteen, cafeteria, etc.)

Qualifikationen

• Completed scientific university degree (M. Sc. or equivalent) in biochemistry or related.
• Experience with protein purification and molecular biology methods.
• Very good knowledge of English or German.

Aufgaben

• Participate in research projects on protein structure and molecular function.
• Supervise practical courses and tutorials in biochemistry and chemistry.
• Organise tasks within the research group.

Kenntnisse

Molecular Biology

Biochemistry

Biophysical Chemistry

Protein Purification

X-ray Crystallography

English

German

Ausbildung

M. Sc. in Biochemistry

Tools

FPLC

HPLC

Jobbeschreibung

TheFaculty of Chemistry, research group Structural Biochemistry, has the following job opening: Research Position (PhD candidate) ID: Wiss25270

• starting: as soon as possible
• part-time 50 %
• salary according to Remuneration level E13 TV-L
• fixed-term

The Structural Biochemistry group investigates the structure-function relationship of proteins, especially bacterial virulence factors and enzymes. The central method for structure determination is X-ray crystallography. We are looking for a person who is enthusiastic about the molecular function of proteins and is eager to work on a research project in this field. Current topics are the type III secretion system of the human pathogenic bacterium Yersinia enterocolitica and flavin-dependent halogenases as potential biocatalysts for sustainable syntheses in Chemistry. Your Tasks

• Participation in research projects on the structure and molecular function of proteins (60%)
  • recombinant protein expression (incl. cloning)
  • protein purification and crystallisation
  • X-ray diffraction experiments, data analysis, structure determination
  • functional analyses (e.g. binding assays, enzyme assays, spectroscopy, etc.)
  • documentation and publication
• Teaching tasks in the supervision of practical courses and tutorials in Biochemistry and Chemistry, 2 LVS (25 %)
• Organisational tasks in the research group (15%)

The employment is conducive to scientific qualification. We offer

• salary according to Remuneration level E13 TV-L
• fixed-term (3 Years) (§ 2 (1) sentence 1 of the WissZeitVG; in accordance with the provisions of the WissZeitVG and the Agreement on Satisfactory Conditions of Employment, the length of contract may differ in individual cases)
• part-time 50 %

• internal and external training opportunities
• variety of health, consulting and prevention services
• reconcilability of family and work
• collegial working environment
• open and pleasant working atmosphere
• exciting, varied tasks
• various offers (canteen, cafeteria, restaurants, Uni-Shop, ATM, etc.)

Your Profile We expect

• completed scientific university degree (M. Sc. or equivalent) in biochemistry or a related natural science subject
• sound knowledge of Biochemistry, Molecular Biology and Biophysical Chemistry
• practical experience with molecular biology methods and recombinant protein expression
• practical experience with protein purification (also using FPLC)
• independent, diligent and committed working style
• very good knowledge of written and spoken English or German
• definite intention to pursue a PhD

Preferred experience and skills

• knowledge in the field of protein structure determination
• practical experience with protein crystallisation and X-ray structure analysis
• practical experience with biophysical methods (e. g. DSF, MST, BLI, ITC, CD, SPR, etc.)
• practical experience with the investigation of protein-protein interactions
• practical experience with HPLC analysis
• very good knowledge of written and spoken English

Application Procedure

We are looking forward to receiving your application. To apply, please preferably use our online form via the application button below.

application deadline: 24.07.2025 Contact
Prof. Dr. Hartmut Niemann
0521-106 6154
[e-mail]
Postal Address
Universität Bielefeld
Biochemie IV
Prof. Dr. Hartmut Niemann
Postfach 10 01 31
33501 Bielefeld Bielefeld University has received a number of awards for its achievements as an equal-opportunity employer and has beenrecognized as a family-friendly university. The university welcomes applications from women. This is particularly true with regardboth to academic and technical posts as well as positions in information technology as well as the skilled crafts and trades.Applications are handled according to the provisions of the state statutes on equal opportunity. Applications from suitably qualifiedhandicapped and severely handicapped persons are explicitly encouraged.At Bielefeld University on request positions can be carried out with reduced working hours as long as this does not conflict with official needs.

TheFaculty of Chemistry, research group Structural Biochemistry, has the following job opening: Research Position (PhD candidate) ID: Wiss25270

• starting: as soon as possible
• part-time 50 %
• salary according to Remuneration level E13 TV-L
• fixed-term

The Structural Biochemistry group investigates the structure-function relationship of proteins, especially bacterial virulence factors and enzymes. The central method for structure determination is X-ray crystallography. We are looking for a person who is enthusiastic about the molecular function of proteins and is eager to work on a research project in this field. Current topics are the type III secretion system of the human pathogenic bacterium Yersinia enterocolitica and flavin-dependent halogenases as potential biocatalysts for sustainable syntheses in Chemistry. Your Tasks

• Participation in research projects on the structure and molecular function of proteins (60%)
  • recombinant protein expression (incl. cloning)
  • protein purification and crystallisation
  • X-ray diffraction experiments, data analysis, structure determination
  • functional analyses (e.g. binding assays, enzyme assays, spectroscopy, etc.)
  • documentation and publication
• Teaching tasks in the supervision of practical courses and tutorials in Biochemistry and Chemistry, 2 LVS (25 %)
• Organisational tasks in the research group (15%)

The employment is conducive to scientific qualification. We offer

• salary according to Remuneration level E13 TV-L
• fixed-term (3 Years) (§ 2 (1) sentence 1 of the WissZeitVG; in accordance with the provisions of the WissZeitVG and the Agreement on Satisfactory Conditions of Employment, the length of contract may differ in individual cases)
• part-time 50 %

• internal and external training opportunities
• variety of health, consulting and prevention services
• reconcilability of family and work
• collegial working environment
• open and pleasant working atmosphere
• exciting, varied tasks
• various offers (canteen, cafeteria, restaurants, Uni-Shop, ATM, etc.)

Your Profile We expect

• completed scientific university degree (M. Sc. or equivalent) in biochemistry or a related natural science subject
• sound knowledge of Biochemistry, Molecular Biology and Biophysical Chemistry
• practical experience with molecular biology methods and recombinant protein expression
• practical experience with protein purification (also using FPLC)
• independent, diligent and committed working style
• very good knowledge of written and spoken English or German
• definite intention to pursue a PhD

Preferred experience and skills

• knowledge in the field of protein structure determination
• practical experience with protein crystallisation and X-ray structure analysis
• practical experience with biophysical methods (e. g. DSF, MST, BLI, ITC, CD, SPR, etc.)
• practical experience with the investigation of protein-protein interactions
• practical experience with HPLC analysis
• very good knowledge of written and spoken English

Application Procedure

We are looking forward to receiving your application. To apply, please preferably use our online form via the application button below.

application deadline: 24.07.2025 Contact
Prof. Dr. Hartmut Niemann
0521-106 6154
[e-mail]
Postal Address
Universität Bielefeld
Biochemie IV
Prof. Dr. Hartmut Niemann
Postfach 10 01 31
33501 Bielefeld Bielefeld University has received a number of awards for its achievements as an equal-opportunity employer and has beenrecognized as a family-friendly university. The university welcomes applications from women. This is particularly true with regardboth to academic and technical posts as well as positions in information technology as well as the skilled crafts and trades.Applications are handled according to the provisions of the state statutes on equal opportunity. Applications from suitably qualifiedhandicapped and severely handicapped persons are explicitly encouraged.At Bielefeld University on request positions can be carried out with reduced working hours as long as this does not conflict with official needs. open as PDF