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Postdoctoral Researcher (f/m/d) for the Collaborative Research Centre “CONCENTRATE” - Enzymolog[...]

Freien Hansestadt Bremen

Bremen

Vor Ort

EUR 45.000 - 55.000

Vollzeit

Vor 9 Tagen

Zusammenfassung

Die Freie Hansestadt Bremen sucht einen Postdoktoranden (w/m/d) für das Collaborative Research Centre CONCENTRATE, das sich auf Enzymologie und Glycomik konzentriert. Die Position beinhaltet die Entwicklung und Unterstützung von Technologien für die glykananalytischen Analysen sowie die Optimierung enzymatischer Prozesse. Bewerber müssen einen Hochschulabschluss in Biochemie oder verwandten Bereichen sowie umfassende Kenntnisse in der Mikrobiologie und exzellente Englischkenntnisse mitbringen.

Leistungen

Jährliche Sonderzahlung
30 Tage Urlaub
Individuelle Einarbeitungsprogramme
Fort- und Weiterbildungsmöglichkeiten
Flexible Arbeitszeiten und Mobilarbeit
Kostenlose soziale und familiäre Beratungsdienste
Aktives Gesundheitsmanagement
Zahlreiche sportliche und kulturelle Aktivitäten

Qualifikationen

  • Abschluss eines wissenschaftlichen Hochschulstudiums (Master/Universitätsdiplom) in Biochemie, Chemie, Biotechnologie oder verwandten Bereichen.
  • Abgeschlossenes Promotionsstudium in der Glykanforschung oder verwandten Fachgebieten.
  • Starke Motivation und die Fähigkeit, in einem interdisziplinären Forschungs- und Bildungsumfeld aktiv zu arbeiten.

Aufgaben

  • Optimierung von Enzymkaskaden für strukturelle und quantitative Analysen von Glykanen.
  • Durchführung von Analysen von Mono- und Oligosacchariden.
  • Veröffentlichung von Ergebnissen in internationalen Fachzeitschriften.

Kenntnisse

Chromatographie
Enzymologie
Glykananalyse
Mikrobiologie
Englischkenntnisse

Ausbildung

Wissenschaftlicher Hochschulabschluss in Biochemie oder verwandten Bereichen

Jobbeschreibung

Postdoctoral Researcher (f/m/d) for the Collaborative Research Centre “CONCENTRATE” - Enzymology & glycomics

The University of Bremen, MARUM - Center for Marine Environmental Sciences - is offering a fixed-term position for a

Postdoctoral Researcher (f/m/d)
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from 1 October 2025 at the earliest for a period of 45 months, until 30 June 2029 at the latest (according to § 2 WissZeitVG)
within the Collaborative Research Centre “CONCENTRATE”.

The position is to be filled with 100% of the regular weekly working hours (39.2 hours/week).

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We are looking for highly motivated candidates to join the newly established Collaborative Research Centre “Carbon Sequestration at Å resolution (CONCENTRATE)”, funded by the German Research Foundation (DFG). This CRC combines the expertise of the University of Greifswald, the University of Bremen, the Max-Planck-Institute for Marine Microbiology Bremen, the Max-Planck-Institute of Colloids and Interfaces Potsdam, the Leibniz Institute for Baltic Sea Research and the Technical University of Berlin.

The aim of CONCENTRATE is to decipher the molecular and microbial processes that lead to the stabilization of glycans in the ocean. In an interdisciplinary approach, the research team combines laboratory experiments with measurements in natural marine habitats. The focus is on the interactions between algae, bacteria, fungi, their glycans and proteins - down to atomic resolution. The elucidation of these microbial and biochemical mechanisms will contribute to a better understanding of carbon fluxes in the oceans.

Within the CRC CONCENTRATE you will work on subproject C03 under the direction of Prof. Jan-Hendrik Hehemann, Carbon Sequestration and Glycobiochemistry. By providing precise glycan measurements, this project supports the CRC’s goal of understanding why some glycans resist microbial degradation and contribute to carbon sequestration.

You will develop, provide and assist with technologies for structure specific glycan analysis in complex communities using, among others, biocatalytic assays, anion exchange chromatography, glycan microarrays, antibodies, and liquid chromatography mass spectrometry. Your project is linked to many other microbiological and biochemical subprojects of the CRC and you will be part of an interdisciplinary network. You will have the opportunity to work on your PhD in a small research group and will be supported by the University's PhD programs. You will also be able to collaborate with national and international research partners.

Your responsibilities:

  • Optimization of enzyme cascades for the structural and quantitative analyses of diverse glycans
  • Mono- and oligosaccharide analysis of enzymatically digested glycans by diverse methods, including fluorophore-assisted carbohydrate electrophoresis, high-performance liquid chromatography mass spectrometry, nuclear magnetic resonance spectroscopy, reducing sugar assays, monoclonal antibodies and high-performance anion-exchange chromatography with pulsed amperometric detection
  • Purification of glycans, such as sulphated mannan and fucan, from laboratory cultures by anion exchange chromatography
  • Sampling of glycans from microbiome experiments by filtration or anion exchange chromatography
  • Discovery of enzymes for degradation of diatom fucan
  • Acquisition, analysis and presentation of scientific data
  • Supervision of technicians and students
  • Publication of the results in international journals
  • The position offers the opportunity for academic qualification
  • Completed scientific university degree (Master/University Diploma) in biochemistry, chemistry, biotechnology or a related field and a completed doctorate in Carbohydrates and their enzymatic breakdown or related subjects. Applicants who are in the final phase of their doctorate will also be considered. Please note that submission of the doctoral degree certificate is mandatory for employment.
  • Solid knowledge in chromatography, enzymology, and glycan analytics
  • A strong background in microbiology is advantageous
  • Excellent written and spoken English
  • Great basic research interest in marine glycobiochemistry
  • High motivation and ability to work actively in an interdisciplinary research and education environment
  • Independent working style, team spirit, helpfulness and reliability

A201-25

15.08.2025

Befristet

We offer

  • Annual special payment ("Christmas bonus"), regular collectively agreed salary increases and additional public service pension scheme (VBL)
  • A crisis-proof, interesting and varied job in a cosmopolitan university
  • 30 days holiday per calendar year
  • A diverse, future-orientated and open corporate culture
  • Support from a collegial, motivated team with a positive working atmosphere
  • Individual induction training
  • The opportunity for further education and training
  • Compatibility of family and career through flexible working hours (flexitime) and the option of mobile working (subject to the general conditions)
  • Free social and family counselling services
  • Active company health management, including the option of discounts at local sports clubs, gyms and swimming pools (EGYM WELLPASS)
  • The option of using a job ticket for public transportation
  • Numerous sports and cultural activities
  • Varied catering options in the student union canteens

Open to unconventional approaches in research and teaching, the University of Bremen has retained its character as a place of short distances for people and ideas since its founding in 1971. With a broad spectrum of subjects, we combine exceptional performance and innovative potential. As an ambitious research university, we stand for research-based learning approaches and a pronounced interdisciplinary orientation. We actively pursue scientific cooperation in a spirit of global partnership.

Today, around 23,000 people learn, teach, research, and work on our international campus. In research and teaching, administration and operations, we are strongly committed to the goals of sustainability, climate justice, and climate neutrality. Our Bremen spirit is expressed in the courage to try new things, in supportive cooperation, in respect and appreciation for each other. With our study and research profile and as part of the European YUFE network, we assume social responsibility in the region, in Europe, and in the world.

The university is family-friendly, diverse and sees itself as an international university. We therefore welcome all applicants regardless of gender, nationality, ethnic and social origin, religion/belief, disability, age, sexual orientation and identity.

As the University of Bremen intends to increase the proportion of female employees in science, women are particularly encouraged to apply. In the case of equal qualifications, women are given priority, unless reasons relating to the person of a competitor prevail.

Disabled applicants will be given priority if their professional and personal qualifications are essentially the same.

Please note that no photos are to be attached to the application documents.

We kindly ask you to send us only copies (no portfolios) of your application documents, as we cannot return them. They will be destroyed after the selection process has been completed.

Any application costs cannot be reimbursed.

For general questions about the personnel selection procedure and for questions about the content of the advertised position, please contact Prof. Dr. Jan-Hendrik Hehemann / +49 421 218 65775 / jhhehemann@marum.de .

Please send your application including a cover letter, CV, copies of degree certificates, as well as a statement of your research interests, scientific background in relation to the position and the contact details of two referees, quoting the reference number A201-25, until 15.08.2025 as a PDF file by unencrypted electronic mail to: bewerbung-a20125@marum.de or by mail to:

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