Postdoctoral Researcher

Universitätsklinikum Ulm; Ulm; On-site; EUR 45,000 - 55,000; Full time

Benefits offered by this job

Salary based on qualification and experience

Benefits according to TV‑L E13

Supportive supervision

Short-term lab visits in Germany and abroad

Job summary

A leading university hospital in Ulm is seeking a Postdoctoral Scientist to join a research group focused on pediatric neurogenomics. Candidates will engage in groundbreaking research on muscular dystrophies, conduct experiments involving animal models, and publish impactful findings. The position offers a collaborative environment with opportunities for professional growth and further training in advanced methodologies. Applicants with a Ph.D. in biology or related fields are encouraged to apply, especially women and disabled candidates.

Qualifications

• Strong interest in drug development in genetically inherited diseases.
• Hands-on experience with animal models desirable.
• Solid background in molecular biology desirable.

Responsibilities

• Discover novel muscular dystrophy-associated genes using OMICs techniques.
• Characterize mouse models for muscular dystrophy pathophysiology.
• Develop antisense oligonucleotides for Duchenne Muscular Dystrophy therapy.
• Create protein quantification techniques including mass spectrometry.
• Collaborate with an international research team.
• Publish impactful original research papers.

Skills

Programming skills

Collaborative project work

Education

Ph.D. in biology or related field

Job description

Professor and Division Head of Pediatric Neurology, Metabolics and Social Pediatrics

Position: Postdoctoral Scientist in the research group for neurogenomics and translational myology of Prof. Dr. Sebahattin Cirak at the University Hospital Ulm.

Location: Large pediatric research center of the Department of Pediatrics and Adolescent Medicine.

Project: Investigating cellular and molecular mechanisms of pediatric neurogenetic disorders and muscular dystrophies. Mainly based novel genomics approaches using patient samples and in‑vitro models.

Responsibilities include:

• Discovery of novel muscular dystrophy‑associated genes and molecular mechanisms using state‑of‑the‑art OMICs techniques (long‑read RNA sequencing, spatial transcriptomics).
• Characterization of mouse models to investigate underlying pathophysiological mechanisms leading to muscular dystrophy.
• Development of novel antisense oligonucleotides for exon‑skipping therapy of Duchenne Muscular Dystrophy in‑vitro and in mdx mice models.
• Development of protein quantification techniques including mass spectrometry.
• Collaborating with an international team under the supervision and leadership of the PI.
• Publishing impactful original research papers.

Offer: Salary based on qualification and experience, plus benefits according to TV‑L E13. The position is for 9 months, with extension possible. Very good scientific environment, broad repertoire of methods, supportive supervision, friendly group. Short‑term visits to other labs in Germany and abroad.

EEO statement: The Board of Directors of the University Hospital Ulm places strong emphasis on gender equality and seeks to increase the proportional representation of women in this field. Thus, applications from female scientists are welcome; suitably qualified women will be given preferential consideration unless other candidates clearly demonstrate superior qualifications. We also welcome applications from disabled candidates, who will be given preferential consideration over other applicants with comparable qualifications.

Qualifications:

• Ph.D. in biology or related field, strong interest in drug development in genetically inherited diseases.
• Hands‑on experience with animal models desirable.
• Solid background in molecular biology desirable.
• Ability to work on multiple projects collaboratively.
• Programming skills preferred.
• Creativity and capability to develop a competitive research project while working autonomously under the supervision of a team leader.

Contact: Prof. Dr. Sebahattin Cirak, University Hospital Ulm, Tel. [phone].