Postdoctoral position for acoustic and microfluidic organoid assembly (f/m/d)

JR Germany; Heidelberg; Vor Ort; EUR 45.000 - 65.000; Vollzeit

Zusammenfassung

An innovative research program is seeking a postdoctoral researcher to develop advanced organoid models using microfluidic technology. This exciting role involves designing experiments, developing microfluidic chips, and analyzing the impact of guided assembly on cell biology. You will collaborate with leading experts in a diverse and interdisciplinary environment, contributing to groundbreaking research in bioengineering. This is a unique opportunity to engage in cutting-edge science that aims to revolutionize disease modeling and organoid research. Join a dynamic team dedicated to pushing the boundaries of biomedical engineering!

Qualifikationen

• Outstanding doctoral degree in relevant fields.
• Strong research record with peer-reviewed publications.

Aufgaben

• Design experiments for organoid formation using microfluidic devices.
• Collaborate with interdisciplinary teams within the POEM network.

Kenntnisse

Microfluidics

Cell Culture

Acoustofluidics

Communication Skills

Ausbildung

Doctoral Degree in Physics

Doctoral Degree in Mechanical Engineering

Doctoral Degree in Electrical Engineering

Doctoral Degree in Biotechnology

Jobbeschreibung

Postdoctoral position for acoustic and microfluidic organoid assembly (f/m/d), Heidelberg

This position is funded by the Carl-Zeiss-Stiftung (CZS) and is part of the collaborative research program "Precision Organoid Engineering for Multi-Organ Interaction Studies (POEM)". The program aims to develop reproducible, micrometer-scale controllable, and cost-efficient disease models through interdisciplinary approaches involving molecular systems engineering, machine learning, biomedicine, and disease modeling.

Responsibilities:

1. Design experiments to assess organoid and assembloid formation using microfluidic devices with ultrasound-directed cell manipulation.
2. Develop microfluidic chips for cell handling and assembly, incorporating ultrasound and exploring other force fields such as light and magnetics.
3. Analyze how guided assembly and force field manipulation influence cell and tumor biology.
4. Collaborate with interdisciplinary teams within the POEM network, including research groups led by Dr. Kai Melde and Dr. Johannes Betge.
5. Integrate findings into automated cell culture processes and assist with the generation and analysis of patient-derived or iPSC-derived organoids.

Qualifications:

• Outstanding doctoral degree in physics, mechanical or electrical engineering, biotechnology, or related fields.
• Strong research record demonstrated through peer-reviewed publications and conference contributions.
• Experience with microfluidics is required; knowledge of acoustofluidics, cell culture, and cell biology is beneficial.
• Excellent communication skills and motivation for organoid research and bioengineering.

Additional Information:

This full-time, non-permanent position is initially funded for 2 years, remunerated according to TV-L, and follows the German Academic Fixed-Term Contract Act. Applications should be sent as a single PDF by May 15th, 2025, to Dr. Kai Melde, including a motivation letter, CV, publications list, research support, teaching experience, research summary, and referees.

Heidelberg University promotes diversity and equal opportunities. Qualified female candidates and persons with severe disabilities are especially encouraged to apply.