Postdoc - Molecular Biology (m/f/d)- Numaferm GmbH

Numaferm; Düsseldorf; Vor Ort; EUR 45.000 - 75.000; Vollzeit

Zusammenfassung

Ein innovatives Biotech-Unternehmen sucht einen motivierten Wissenschaftler oder Postdoktoranden, um das Team für Molekularbiologie und Bibliotheksdesign zu verstärken. In dieser spannenden Rolle gestalten Sie DNA-Bibliotheken und tragen zur Entwicklung bahnbrechender Technologien in der synthetischen Biologie bei. Sie arbeiten in einem dynamischen, kollaborativen Umfeld und haben die Möglichkeit, an bedeutenden Projekten zu arbeiten, die reale Anwendungen in der Medizin und Biotechnologie haben. Diese Position bietet Ihnen die Chance, Ihre Ideen einzubringen und mit dem Unternehmen zu wachsen.

Leistungen

Dynamisches Arbeitsumfeld

Flache Hierarchien

Flexibilität

Bedeutende Projekte

Möglichkeit zur Weiterentwicklung

Qualifikationen

• Erfahrung in der molekularen Klonierung und Konstruktion von Genbibliotheken.
• Fähigkeit zur Anwendung bioinformatischer Werkzeuge zur Sequenzanalyse.

Aufgaben

• Design und Konstruktion von DNA-Bibliotheken mit fortschrittlichen Klonierungstechniken.
• Unterstützung interner Forschung und externer Kundenprojekte.

Kenntnisse

Molekularbiologie

Klonierungstechniken

Bioinformatik

DNA/RNA-Manipulation

PCR

Rekombinante Proteinexpression

Kommunikationsfähigkeiten

Ausbildung

PhD in Molekularbiologie

PhD in Biotechnologie

PhD in Synthetischer Biologie

Tools

Gibson Assembly

BSA Klonierung

Gateway Klonierung

CRISPR/Cas9

Jobbeschreibung

About Numaferm

Numaferm is a fast-growing biotech company, pioneering innovation in peptide and protein production through recombinant expression technologies. With a strong scientific foundation and a commercial mindset, we are driving impactful solutions for clients across pharma, biotech, and industrial sectors. At Numaferm, you’ll have the opportunity to grow with us and shape the future of molecular biology.

Job Title: Scientist / PostDoc - Molecular Biology, Library Design & Construction (m/f/d)

Location: Düsseldorf, Germany

Company: Numaferm GmbH

Job Type: Fixed-Term (1 Year), Full-Time

Start Date: As soon as possible

Your Role

We are looking for a motivated and creative Scientist or Postdoctoral Researcher to join our Molecular Biology & Library Design team. You will play a key role in the design, construction, and screening of DNA libraries and molecular toolsets. You will also contribute to innovative internal R&D and support customer-driven projects.

This role is an excellent opportunity to work on cutting-edge technologies at the interface of synthetic biology, molecular design, and bioinformatics. The position is lab-based, including data analysis, concept development, and direct project communication with clients.

Key Responsibilities

1. Laboratory & Technical Work
   
   • Design and construct gene libraries using advanced cloning techniques such as Gibson Assembly, BSA Cloning, Gateway Cloning, and others
   • Apply bioinformatic tools to design gene constructs, optimize sequences, and analyze data
   • Perform molecular biology workflows including DNA/RNA manipulation, PCR, sequencing, and recombinant protein expression
   • Support both internal research and external client projects with high scientific and technical standards
2. Client Interaction & Communication
   
   • Serve as a scientific point of contact during customer project execution
   • Present designs, timelines, and results to clients in a professional and clear manner
   • Contribute to proposals, reports, and presentations
3. Conceptual & Strategic Development
   
   • Develop and implement innovative molecular biology workflows
   • Evaluate new technologies for molecular and protein engineering

Required Qualifications

1. PhD in Molecular Biology, Biotechnology, Synthetic Biology, or a related field
2. Proven hands-on experience in molecular cloning and construct design
3. Familiarity with gene library design and generation
4. Experience with bioinformatic tools for DNA/RNA sequence analysis and optimization
5. Strong communication skills and ability to work collaboratively
6. Fluent in English and German (written and spoken)

Additional Desired Qualifications

1. Experience with the amber stop codon strategy and genetic code expansion
2. Expertise in homologous recombination for gene knock-in/knock-out
3. Expertise with E. coli cell-free expression systems
4. Practical experience with CRISPR/Cas9 genome editing
5. Hands-on knowledge of E. coli small- to mid-scale fermentation
6. Familiarity with recombinant protein expression in microbial systems
7. Experience with bioinformatic tools for protein design and optimization, including rational design or AI-driven approaches (e.g., structure prediction, stability engineering, in silico mutagenesis)

What We Offer

1. A one-year employment contract with a clear potential for extension
2. A dynamic, collaborative work environment in a high-growth biotech company
3. Flat hierarchies, flexibility, and the chance to contribute your own ideas
4. Meaningful projects with real-world application in medicine and biotech
5. The opportunity to grow with the company and take on new responsibilities