Postdoc - Innovative Biopredictive Dissolution

Boehringer Ingelheim GmbH; Biberach an der Riß; On-site; EUR 50,000 - 70,000; Part time

Benefits offered by this job

Benefits and wellbeing package

Disability-inclusive recruitment

Job summary

Boehringer Ingelheim GmbH in Germany seeks a curious Postdoc to advance biopredictive dissolution approaches for challenging compounds and advanced oral formulations. The role blends lab work, mechanistic interpretation and digital tools to inform oral drug product development.

You will collaborate with formulation, biopharmaceutics, pharmacokinetics, modeling and regulatory sciences, publish findings, and participate in international scientific exchanges.

Qualifications

• PhD in Pharmacy, Pharmaceutical Sciences, Chemistry, Food Science or a related discipline.
• Hands-on experience in dissolution testing, oral formulation development, biopharmaceutics or a related experimental field.
• Experience in analytical method development using HPLC/UPLC, UV spectroscopy; solid-state or particle characterization, imaging or laboratory automation advantageous.
• Knowledge of oral drug absorption and its relation to formulation performance; familiarity with IVIVR/IVIVC, PBPK/ PBPK modeling or regulatory biopharmaceutics advantageous.
• Ability to independently plan and conduct experiments; interest in AI-enabled knowledge discovery and data analysis.
• Excellent scientific communication, presentation and technical writing in English; German is advantageous but not required.

Responsibilities

• Independently design, conduct and evaluate studies to develop physiologically relevant, biopredictive dissolution approaches for challenging compounds and advanced oral formulations.
• Investigate dissolution, supersaturation and precipitation to derive mechanistic insights affecting in vitro performance.
• Build on insights to apply developed approaches to drug development questions and assess applicability and limitations.
• Develop practical recommendations and best practices for oral drug product development.
• Use digital, data-driven and computational tools to analyze complex datasets and support evidence-based decisions.
• Collaborate with formulation development, biopharmaceutics, pharmacokinetics, modeling and regulatory sciences.
• Communicate findings through scientific reports, peer-reviewed publications and presentations.

Skills

Dissolution testing

Oral formulation development

Biopharmaceutics

Supersaturation

Precipitation

IVIVR/IVIVC modeling

Statistical data analysis

Education

PhD in Pharmacy/Pharmaceutical Sciences

Tools

HPLC/UPLC

UV spectroscopy

Imaging

Laboratory automation

Job description

The Position

How can experimental dissolution science and digital approaches help us better understand the performance of tomorrow’s oral medicines? We are seeking a curious and motivated Postdoc to join our Biopharmaceutics and Dissolution Sciences team in Biberach. You will lead a research project focused on advancing biopredictive dissolution approaches for challenging compounds and advanced oral formulations.

Combining hands-on laboratory research, mechanistic interpretation and modern digital tools, you will explore how drug substance properties, formulation attributes and experimental conditions influence in vitro performance and support oral formulation development.

Working with multidisciplinary experts and state-of-the-art technologies, you will build your independent research profile and gain experience in pharmaceutical development, with opportunities for peer-reviewed publications and international scientific exchange.

This position is part time eligible with 80 %.

Postdoc: This Position is limited for 2 years.

Note: To make it easier to find our job advertisements, we use the usual designation \"postdoc\". Of course, this advertisement is not only addressed to applicants directly after completing their doctorate, but to all qualified candidates.

Tasks & responsibilities

• You independently design, conduct and evaluate studies to develop physiologically relevant, biopredictive dissolution approaches for challenging compounds and advanced oral formulations.


• By investigating dissolution, supersaturation and precipitation, you derive mechanistic insights into how drug substance properties, formulation attributes, manufacturing variables and test conditions influence in vitro performance.


• Building on these insights, you apply the developed approaches to drug development questions and critically assess their applicability and limitations.


• Your findings enable you to develop practical recommendations and best practices for oral drug product development.


• Using digital, data-driven and computational tools, you analyze complex datasets and support evidence-based decisions.


• As part of a multidisciplinary environment, you collaborate with experts in formulation development, biopharmaceutics, pharmacokinetics, modeling and regulatory sciences.


• Through scientific reports, peer-reviewed publications and presentations, you communicate your research findings to internal teams and at international conferences.

Requirements

• PhD in Pharmacy, Pharmaceutical Sciences, Chemistry, Food Science or a related discipline.


• Hands-on experience in dissolution testing, oral formulation development, biopharmaceutics or a related experimental field. Experience with poorly soluble compounds, amorphous solid dispersions, supersaturation or precipitation is advantageous.


• Experience in analytical method development using techniques such as HPLC/UPLC, UV spectroscopy or comparable methods. Experience with solid-state or particle characterization, imaging or laboratory automation is advantageous.


• Sound understanding of oral drug absorption and its relationship to drug substance properties, formulation performance and gastrointestinal conditions. Knowledge of physiologically relevant dissolution testing, IVIVR/IVIVC, PBBM/PBPK modeling or regulatory biopharmaceutics is advantageous.


• Ability to independently plan and conduct experiments, critically analyze complex datasets and draw clear scientific conclusions. Interest or experience in computational tools, scientific informatics, knowledge management or AI-enabled knowledge discovery is desirable. Experience with statistical data analysis is advantageous.


• Scientific curiosity, a proactive and well-organized working style, and the ability to collaborate across disciplines and functions. Excellent scientific communication, presentation and technical writing skills in English. German language skills are advantageous but not required.

As part of our commitment to transparency and fairness, salary information will be shared during the recruitment process. We also offer a comprehensive benefits and wellbeing package.

Applications from persons with severe disabilities are warmly welcomed. In cases of equal qualifications, such applicants will be given preferential consideration in the selection process.

Ready to contact us?

If you have any questions about the job posting or process - please contact our HR Direct Team, Tel: [phone] or via mail: [e-mail]

Recruitment process:
Step 1: Online application - The job posting is presumably online until November 11, 2026. We reserve the right to take the posting offline beforehand. Applications up to November 04, 2026 are guaranteed to be considered.
Step 2: Virtual meeting in the period from mid of November till end of November
Step 3: On-site interviews beginning mid of December