Postdoc - Innovative Biopredictive Dissolution

Boehringer Ingelheim Pharma GmbH & Co. KG

Biberach an der Riß

On-site

EUR 52,000 - 70,000

Part time

8 days ago

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Job summary

Boehringer Ingelheim Pharma GmbH & Co. KG in Biberach is seeking a postdoc to advance biopredictive dissolution approaches for challenging compounds and advanced oral formulations.

You will combine lab work, mechanistic interpretation and digital tools to understand factors influencing in vitro performance. You will collaborate across biopharmaceutics, pharmacokinetics, modeling and regulatory sciences, publish results, and contribute to oral drug product development within a multidisciplinary

Qualifications

  • PhD in Pharmacy, Pharmaceutical Sciences, Chemistry, Food Science or related discipline.
  • Hands-on experience in dissolution testing, oral formulation development, biopharmaceutics or related field.
  • Experience with poorly soluble compounds, amorphous solid dispersions, supersaturation or precipitation is advantageous.
  • Experience with analytical method development using HPLC/UPLC, UV spectroscopy or comparable methods.
  • Knowledge of IVIVC/PBBM modeling or regulatory biopharmaceutics is advantageous.
  • Excellent scientific communication, presentation and technical writing skills in English; German advantageous.

Responsibilities

  • Independently design, conduct and evaluate studies to develop biopredictive dissolution approaches for challenging compounds and oral formulations.
  • Investigate dissolution, supersaturation and precipitation to derive mechanistic insights and influence formulation attributes and test conditions.
  • Apply developed approaches to drug development questions and assess applicability and limitations.
  • Develop practical recommendations and best practices for oral drug product development.
  • Use digital, data-driven and computational tools to analyze complex datasets and support decisions.
  • Collaborate with experts in formulation development, biopharmaceutics, pharmacokinetics, modeling and regulatory sciences.
  • Communicate findings through scientific reports, peer-reviewed publications and presentations.

Skills

Dissolution testing
Biopharmaceutics
Formulation development
Analytical methods
Computational tools
English writing

Education

PhD in Pharmacy/Pharmaceutical Sciences

Tools

HPLC/UPLC
UV spectroscopy
Solid-state analysis
Lab automation

Job description

Boehringer Ingelheim is a biopharmaceutical company active in both human and animal health. As one of the industry's top investors in research and development, the company focuses on developing innovative therapies that can improve and extend lives in areas of high unmet medical need. Independent since its foundation in 1885, Boehringer takes a long‑term perspective, embedding sustainability along the entire value chain. Our approximately 54,500 employees serve over 130 markets to build a healthier and more sustainable tomorrow. Learnmore atwww.boehringer-ingelheim.com

The Position

How can experimental dissolution science and digital approaches help us better understand the performance of tomorrow's oral medicines? We are seeking a curious and motivated Postdoc to join our Biopharmaceutics and Dissolution Sciences team in Biberach. You will lead a research project focused on advancing biopredictive dissolution approaches for challenging compounds and advanced oral formulations.

Combining hands‑on laboratory research, mechanistic interpretation and modern digital tools, you will explore how drug substance properties, formulation attributes and experimental conditions influence in vitro performance and support oral formulation development.

Working with multidisciplinary experts and state‑of‑the‑art technologies, you will build your independent research profile and gain experience in pharmaceutical development, with opportunities for peer‑reviewed publications and international scientific exchange.

Discover our Biberach site: xplorebiberach.com

This position is limited for 2 years.

This position is part time eligible with 80%.

Postdoc: This Position is limited for 2 years.

Note: To make it easier to find our job advertisements, we use the usual designation "postdoc". Of course, this advertisement is not only addressed to applicants directly after completing their doctorate, but to all qualified candidates.

Tasks & responsibilities
  • You independently design, conduct and evaluate studies to develop physiologically relevant, biopredictive dissolution approaches for challenging compounds and advanced oral formulations.
  • By investigating dissolution, supersaturation and precipitation, you derive mechanistic insights into how drug substance properties, formulation attributes, manufacturing variables and test conditions influence in vitro performance.
  • Building on these insights, you apply the developed approaches to drug development questions and critically assess their applicability and limitations.
  • Your findings enable you to develop practical recommendations and best practices for oral drug product development.
  • Using digital, data‑driven and computational tools, you analyze complex datasets and support evidence‑based decisions.
  • As part of a multidisciplinary environment, you collaborate with experts in formulation development, biopharmaceutics, pharmacokinetics, modeling and regulatory sciences.
  • Through scientific reports, peer‑reviewed publications and presentations, you communicate your research findings to internal teams and at international conferences.
Requirements
  • PhD in Pharmacy, Pharmaceutical Sciences, Chemistry, Food Science or a related discipline.
  • Hands‑on experience in dissolution testing, oral formulation development, biopharmaceutics or a related experimental field. Experience with poorly soluble compounds, amorphous solid dispersions, supersaturation or precipitation is advantageous.
  • Experience in analytical method development using techniques such as HPLC/UPLC, UV spectroscopy or comparable methods. Experience with solid‑state or particle characterization, imaging or laboratory automation is advantageous.
  • Sound understanding of oral drug absorption and its relationship to drug substance properties, formulation performance and gastrointestinal conditions. Knowledge of physiologically relevant dissolution testing, IVIVR/IVIVC, PBBM/PBPK modeling or regulatory biopharmaceutics is advantageous.
  • Ability to independently plan and conduct experiments, critically analyze complex datasets and draw clear scientific conclusions. Interest or experience in computational tools, scientific informatics, knowledge management or AI‑enabled knowledge discovery is desirable. Experience with statistical data analysis is advantageous.
  • Scientific curiosity, a proactive and well‑organized working style, and the ability to collaborate across disciplines and functions. Excellent scientific communication, presentation and technical writing skills in English. German language skills are advantageous but not required.

As part of our commitment to transparency and fairness, salary information will be shared during the recruitment process. We also offer a comprehensive benefits and wellbeing package.

Applications from persons with severe disabilities are warmly welcomed. In cases of equal qualifications, such applicants will be given preferential consideration in the selection process.

With us, you can develop your own path in a company with a culture that knows our differences are our strengths - and break new ground in the drive to make millions of lives better.

Here, your development is our priority. Supporting you to build a career as part of a workplace that is independent,authenticand bold, while tackling challenging work in a respectful and friendly environment where everyone is valued and welcomed.

Alongside, you have access to programs and groups that ensure your health and wellbeing are looked after - as we make major investments to drive global accessibility to healthcare.By being part of a team that is constantly innovating,you'llbe helping to transform lives for generations.

Want to learn more? Visithttps://www.boehringer-ingelheim.com

If you have any questions about the job posting or process - please contact our HR Direct Team, Tel: +49 (0) 6132 77-3330 or via mail: hr.de@boehringer-ingelheim.com

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