PhD Student (gn •) Immunology

Universitätsklinikum Münster; Senden; Vor Ort; EUR 40.000 - 60.000; Teilzeit

Zusammenfassung

A leading healthcare research institute is seeking a PhD Student in Immunology. This position focuses on investigating receptor involvement in metabolic diseases, particularly atherosclerosis. Candidates should have a Master's degree in Biological Sciences and a strong background in immunology. Enthusiasts who are eager to conduct experiments and contribute to scientific knowledge in a collaborative environment are encouraged to apply. The role offers comprehensive benefits and opportunities for professional growth.

Leistungen

Health insurance

Pension plan

Family support services

Professional growth opportunities

Qualifikationen

• Strong understanding of chronic inflammatory conditions.
• Hands-on experience in laboratory techniques.
• Ability to work independently and collaboratively.

Aufgaben

• Design and conduct experiments on metabolic diseases.
• Collaborate to develop models of atherosclerosis.
• Analyze and publish experimental data.

Kenntnisse

Background in immunology

Flow-cytometry experience

Cell-culture knowledge

Good communication skills in English

Ausbildung

MSc in Biological Sciences

Tools

Flow cytometry

Immunofluorescence microscopy

Cell culture

Jobbeschreibung

PhD Student – Immunology

Fixed‑term of 3 years | Part‑time (65 % or 25 hours/week) | Salary according to TV‑L, group 13 | Institute for Experimental Pathology, University of Münster | Job ID 11273

Overview

We are UKM. Our mission is to advance healthcare through research and teaching. We invite you to join the Institute for Experimental Pathology to contribute to cutting‑edge science.

Project

In a project funded by the IZKF, the newly established group of Dr. Mariano Malamud investigates inhibitory receptors in chronic inflammatory conditions. The focus of this PhD project is a newly described receptor (Malamud et al., Nature 2024) that regulates cellular responses in obesity and its metabolic sequelae, especially atherosclerosis. The work builds on our expertise in neutrophil‑driven sterile inflammation (O. Söhning et al., Nat Rev Immunol 2017; Silvestre‑Roig et al., Nature 2019).

Your Tasks

• Design and conduct experiments using state‑of‑the‑art methods.
• Animal models of metabolic disease and atherosclerosis.
• Flow‑cytometric analysis of immune cells from murine tissues using full‑spectrum flow cytometry.
• Immunohistological staining and imaging with multiplexed immunohistochemistry.
• Biochemical assays for cytokines and other inflammatory mediators.
• Cell‑culture experiments (primary cells and cell lines).
• Collaborate across disciplines to build a comprehensive model of atherosclerosis pathophysiology.
• Analyze, interpret, and publish data; present results at seminars, workshops, and conferences.
• Contribute to manuscript preparation.

What We Expect

• MSc in Biological Sciences.
• Strong background in immunology.
• Hands‑on experience in at least one of: flow‑cytometry (phenotyping/sorting), immunofluorescence microscopy, histopathology, or cell‑culture of primary cells/lines.
• Good communication skills in English; German proficiency desirable but not required.
• Independent working style with effective collaboration.
• Commitment to ongoing training and methodological development.

What We Offer

• Comprehensive benefits including health insurance, pension plan, and family support services.
• Access to world‑class infrastructure, equipment, and resources.
• Opportunities for professional growth, networking, and international collaboration.
• Supportive, innovative, and interdisciplinary environment.

Application

Apply via our career portal until 29 Oct 2025. Please submit:

• Cover letter (max. 2 pages) highlighting relevant experience and career goals.
• Curriculum vitae with publication list and academic record.
• Contact details for two referees familiar with your scientific achievements.

Contact: Mariano Malamud, [e-mail]

Location

Universitätsklinikum Münster
Albert‑Schweitzer‑Campus 1, Gebäude D5
48149 Münster
www.ukm.de