PhD student (f/m/x) in the field of Neuroimmunology

Dzne; Bonn; Vor Ort; EUR 30.000 - 35.000; Vollzeit

Zusammenfassung

A leading research center in Bonn is seeking a motivated PhD student for a project studying neuroinflammation linked to Alzheimer's disease. The role involves diverse research methodologies, collaborative teamwork, and a supportive environment focused on innovation and professional growth.

Leistungen

Flexible working hours

30 days of holiday

Health promotion programs

Professional development trainings

Family-friendly culture

Onboarding support

Regular seminars and conferences

Qualifikationen

• MSc degree in Immunology, Neuroscience, or Biology is required.
• Experience in cell culture, immunology, or neuroscience research is beneficial.
• Fluency in English for effective communication.

Aufgaben

• Conduct research on microglia-mediated neuroinflammation relating to Alzheimer's disease.
• Use cell cultures, animal models, and patient samples for experimental studies.
• Perform immune activation assays and advanced techniques like RNA sequencing.

Kenntnisse

Cell culture

Biochemistry techniques

Immunohistochemistry

Flow cytometry

Fluency in English

Animal experiments

Ausbildung

MSc degree in Immunology, Neuroscience, Biology

Jobbeschreibung

PhD student (f/m/x) in the field of Neuroimmunology, Bonn

Client:

Location:

Bonn, Germany

Job Category:

Other

-

EU work permit required:

Yes

Job Reference:

Job Views:

5

Posted:

23.06.2025

Expiry Date:

07.08.2025

Job Description:

We are seeking an enthusiastic and motivated PhD student to conduct research at the interface of neuroscience and immunology.

The student will join the ‘Translational Neuroimmunology’ research group, led by Dr. Róisín McManus, based at the DZNE in Bonn, affiliated with the Institute of Innate Immunity at the University Hospital Bonn and the ImmunoSensation2 Cluster of Excellence.

The research focuses on understanding how microglia-mediated neuroinflammation contributes to Alzheimer’s disease progression, examining immune signaling and metabolic changes that modulate microglial function and disease outcomes.

Recent work indicates that a western diet can induce lipid changes activating microglia and causing neuroinflammation. Using animal models, cell cultures, and patient samples, the PhD project aims to unravel innate immune pathways mediating these neuroinflammatory changes, contributing to Alzheimer’s disease understanding.

This position involves cell culture work with murine and human cells, immune activation assays, and advanced techniques (metabolic assays, flow cytometry, fluorescence imaging, RNA sequencing, biochemical techniques like western blot). The successful candidate will assess the impact of western diet on microglial activity both in vivo, ex vivo, and in vitro, employing diet treatments, pharmacological inhibition, and genetic approaches.

• A MSc degree in Immunology, Neuroscience, Biology, or a related field
• Experience in animal experiments and immunology, neuroscience, or cell metabolism research is beneficial
• FELASA accreditation is a plus
• Hands-on experience in cell culture, biochemistry techniques, immunohistochemistry, or flow cytometry is desirable
• Fluency in English for communication, writing, and presentation
• Enthusiasm for innovative techniques
• Ability to work in an interdisciplinary, international team

What our employees value

• Innovation and internationality: modern infrastructure, laboratory equipment, and opportunities for international exchange
• Work-life balance: flexible hours, mobile work, 30 days holiday, and festive days off
• Family-friendly culture: parent-child offices, family services, daycare cooperation
• Health promotion: extensive health programs in partnership with Sozialwerk.Bund
• Development focus: tailored training and HR development meetings
• Remuneration: according to TVöD-Bund, including bonuses and pension schemes
• Onboarding: personalized support for a smooth start
• Work environment: campus with greenery, parking, public transport, and on-site restaurant
• Seminars and conferences: regular seminars and opportunities to present research

This position is initially limited to two years.

Applications must be submitted via our portal; email applications are not accepted.

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