PhD Student - 3D organization of tumor microenvironment in primary and metastatic prostate cancer

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PhD Student - 3D organization of tumor microenvironment in primary and metastatic prostate cancer, Frankfurt

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Client:

Location:

Frankfurt, Germany

Job Category:

Other

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EU work permit required:

Yes

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Job Reference:

ad1b7df23e1c

Job Views:

2

Posted:

28.04.2025

Expiry Date:

12.06.2025

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Job Description:

PhD Student - 3D organization of tumor microenvironment in primary and metastatic prostate cancer

(We are targeting applicants of all genders)
Full-time | limited | Announcement number: -4

The Dr. Senckenberg Institute of Pathology (SIP) is a central unit of the University Hospital Frankfurt responsible for patient-oriented diagnostics and research. SIP utilizes a range of morphology and molecular-based cutting-edge technologies to analyze over patient samples every year. The scope of SIP is to provide state-of-the-art diagnostics and develop novel biomarkers to improve patient care.

Project Description

Prostate Cancer (PCa) is one of the most frequent and lethal tumor types in men. This project aims at uncovering the mechanisms through which PCa cells alter their local tissue microenvironment to promote primary tumor progression and metastatic dissemination. Using multiomics approaches and multiplex tissue imaging on patient samples and animal models, we will develop biomarkers for improved PCa classification and response to treatment. In addition, we will quantify the anatomical organization of the tumor microenvironment in a curated cohort of metastatic PCa patients, to unravel and functionally assess crosstalk mechanisms that support metastasis.

Who You Are

• Master’s degree in Biomedical, Life Sciences, or equivalent
• Basic experience in laboratory techniques (i.e., molecular biology)
• Background in immunofluorescence microscopy and prostate cancer are a plus
• Passion for discovery, collaborative spirit, and good communication skills
• Good knowledge of MS-Office
• Good knowledge of spoken and written English
• Due to legal regulations, valid proof of measles immunity / vaccination is required.

What We Offer

• Collective agreement: In addition to an attractive salary based on a collective agreement with an annual special payment, hours per week, and days of vacation, you benefit from long-term security through company pension schemes.
• Mobility: Free public transport in all Hessen (Free State Ticket Hessen)
• Campus: Our attractive university hospital campus offers a modern cafeteria, various cafes, and opportunities to rest in numerous green spaces. A walk along the riverside of the Main offers relaxation during breaks.
• Work-Life Balance: Part-time employment is possible. We offer childcare in our daycare center (more information can be found here), and childcare during holidays.
• Health Promotion: Benefit from our attractive health offers. We provide regular online and face-to-face courses on nutrition, relaxation, sports, and exercise.
• Professional development: Internal and external training for your professional development.

Disabled applicants are preferred if they have the same personal and professional qualifications.