PhD Project "Cardiac chromatin biology" (Gilsbach_0125) - Heidelberg University

Euraxess; Heidelberg; Vor Ort; EUR 45.000 - 55.000; Vollzeit

Zusammenfassung

A leading research lab at Heidelberg University seeks a motivated PhD candidate. This fully funded position focuses on advancing heart disease treatment strategies through innovative genomic research. Join a dynamic team and work in a state-of-the-art facility at a prestigious university.

Qualifikationen

• MSc degree in related fields required.
• Interest in chromatin biology and gene regulation.
• Prior experience with genomics or CRISPR is a plus.

Aufgaben

• Conduct research on heart disease mechanisms.
• Utilize in vitro and in vivo pre-clinical models.
• Combine advanced genomic analysis approaches.

Kenntnisse

Molecular biology

Epigenetics

Chromatin biology

Gene regulation

Disease modeling

Ausbildung

MSc degree in molecular biology, epigenetics, cardiovascular science, or computational biology

Tools

Genomics

Bioinformatics

CRISPR technologies

Jobbeschreibung

HBIGS Heidelberg Biosciences International Graduate School

Organisation/Company HBIGS Heidelberg Biosciences International Graduate School Department Dept. for Biosciences Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country Germany Application Deadline 31 Jul 2025 - 23:55 (Europe/Berlin) Type of Contract Temporary Job Status Full-time Hours Per Week 40 Offer Starting Date 1 Aug 2025 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

We are seeking a highly motivated and creative PhD candidate to join the Gilsbach lab (gilsbachlab.de) at Heidelberg University, ranking among the top three universities in Germany. The PhD position is fully funded with a competitive salary (TVL-13, 65%).


The available research projects aim to understand and develop strategies to treat heart disease. You will combine epigenetic (e.g. C&T, ChIP-seq, ATAC-seq), chromatin interaction analysis (Hi-C) and single-cell approaches to unravel regulatory mechanisms of heart function and disease, including the impact of disease-associated non-coding variants. CRISPR-based functional genomics will allow you to explore and steer the regulatory mechanisms of heart disease. These studies will take advantage of in vitro and in vivo pre-clinical models, including hiPSC-derived systems.

• MSc degree in molecular biology, epigenetics, cardiovascular science, computational biology, or a related field
• A strong interest in chromatin biology, gene regulation, and/or disease modeling
• Prior experience with genomics, bioinformatics, or CRISPR technologies is a plus, but not mandatory

Languages ENGLISH Level Good

Additional Information

The lab is located at the Institute of Experimental Cardiology in a new research building with cutting-edge facilities hosting several cardiovascular research groups forming a highly interactive and dynamic research infrastructure.

Number of offers available 1 Company/Institute University Hospital Heidelberg, Internal Medicine VIII, Inst. Experimental Cardiology Country Germany City Heidelberg Postal Code 69120 Street Im Neuenheimer Feld 669 Geofield