PhD and Technical Assistant Positions in RNA Localization and Function

PhDFinder; Frankfurt; Vor Ort; EUR 60.000 - 80.000; Vollzeit

Zusammenfassung

The Dumbović Lab at Goethe University Frankfurt is seeking a PhD student to investigate RNA biology, specifically focusing on TERT RNA. This role includes cutting-edge techniques like live-cell RNA imaging and CRISPR, contributing to advancements in the understanding of RNA localization and function.

Leistungen

Collaborative research environment

Access to advanced technologies

Training opportunities

Engagement with Cluster of Excellence TRR267

Qualifikationen

• Background in molecular biology required.
• Strong interest in RNA biology.
• Computational expertise is advantageous.

Aufgaben

• Study regulation of intron retention and RNA localization in TERT RNA.
• Employ techniques including live-cell RNA imaging and CRISPR-based editing.
• Identify principles of RNA localization and function in iPS cells.

Kenntnisse

Molecular Biology

RNA Biology

Ausbildung

PhD

Jobbeschreibung

University: Goethe University Frankfurt

Country: Germany

Deadline: Not specified

The Dumbović Lab at Goethe University Frankfurt is seeking applications for a PhD student (experimental or computational) and a Technical Assistant to join a research project investigating RNA biology, with a particular focus on the subcellular localization of Telomerase Reverse Transcriptase (TERT) RNA.

Project Overview

– Study the regulation of intron retention and RNA localization in TERT RNA.

– Employ techniques including live-cell RNA imaging, CRISPR-based editing, and RNA–protein interaction mapping.

– Aim to identify general principles of RNA localization and function in induced pluripotent stem (iPS) cells.

Requirements

– Background in molecular biology; computational expertise is advantageous.

– Demonstrated interest in RNA biology and innovative research.

Benefits

– Collaborative and diverse research environment.

– Access to advanced technologies and training opportunities.

– Engagement with the Cluster of Excellence TRR267 (non-coding RNAs in the cardiovascular system) and SCALE initiatives.

Application Instructions

Interested candidates should send a cover letter and CV (combined as a single PDF) to [e-mail].

For further information, please visit the lab website: www.gdumboviclab.org

Reference publications: https://doi.org/10.1073/pnas.1908275116 and https://doi.org/10.1038/s41467-021-23221-w

Join a dynamic team at the forefront of RNA research.