Master Thesis in Cancer Research - Department of Medicine 2, Hematology and Oncology

Universitätsklinikum Frankfurt; Deutschland; Vor Ort; EUR 20.000 - 35.000; Vollzeit

Zusammenfassung

The Department of Medicine 2 at Universitätsklinikum Frankfurt is seeking candidates for a master's level research position in Hematology/Oncology. The role involves cutting-edge research on cancer vulnerabilities focusing on molecular biology techniques and offers a supportive academic environment.

Leistungen

Collective labour agreement TV GU

International work environment

Excellent supervision by experienced staff

Qualifikationen

• Enthusiasm for biomedical research and oncology.
• Experience in molecular biological techniques is advantageous.
• Valid proof of measles immunity required.

Aufgaben

• Conduct molecular biology tasks including Western Blotting and flow cytometry.
• Perform genetic modification of cancer cell lines using CRISPR-Cas9.
• Analyze data and generate scientific figures.

Kenntnisse

Teamwork

Cell and Molecular Biology

Data Analysis

Experimental Lab Work

Fluent in English

MS-Office

Ausbildung

University Master's Program in Biology, Biochemistry or related discipline

Jobbeschreibung

...you're in the middle of it

The Department of Medicine 2, Hematology / Oncology at the Goethe University Hospital Frankfurt offers the entire spectrum of diagnostics and therapy of malignant diseases as well as a research program focusing on several cancer entities. The research laboratory of Professor Thomas Oellerich is part of the Frankfurt Cancer Institute and focuses on oncogenic signaling and therapy resistance mechanisms in lymphoma and acute myeloid leukemia.
The lab is furthermore funded by the German Cancer Consortium (DKTK), which was founded in 2012 as one of the six German Centers of Excellence for Health Research (DZG). DKTK aims at bringing promising results from cancer research faster into clinical development and patient care. In the DKTK more than 20 academic research institutions and university hospitals at seven partner sites cooperate with each other and the German Cancer Research Center (DKFZ) in Heidelberg as the core center (https://dktk.dkfz.de/standorte/frankfurt-mainz ).

Your Role:

The project focuses on deciphering a novel cancer vulnerability in Lymphoma. The gene of interest is involved in ubiquitin-like protein (UBL) signaling that seems to influence B-cell development.

• Molecular biology tasks include Western Blotting, cell culture, DNA-damage and replication assays, flow cytometry and image-based assays.
• Genetic modification of cancer cell lines utilizing CRISPR-Cas9 and shRNA-mediated knockdowns
• State-of-the-Art advanced techniques such as proximity-labeling, MassSpec proteomics, RNAseq
• Data analysis, figure generation and scientific presentations

... your skills are what we're looking for

• Enrolled in a university master program in biology, biochemistry or a related discipline
• Enthusiasm and fascination for biomedical research, oncology, cell and molecular biology
• High motivation for experimental lab work
• Experiences in cell and molecular biological as well as biochemical lab techniques might be of advantage
• Ability to work in a team, sense of responsibility and proactivity
• Basic knowledge in MS-Office (Word, Excel)
• Fluent in English
• Due to legal regulations, valid proof of measles immunity / measles vaccination is required

... you'll be offered a lot

• Collective labour agreement TV GU
• International and cosmopolitan working environment
• Excellent tandem supervision by a PhD student (Ria Mainkar) and a Team Leader (Dr. Ramesh K Krishnan)
• Scientific education including the management of scientific literature, a bi-weekly journal club, good scientific presentation and publication practice
• Uniklinik-Campus, Mensa, Cafés
• Insights: Instagram , YouTube , LinkedIn
• FAQ's for new employees

It's time to join our team!

Contact: Dr. Niklas Dienstbier (Team Lead - Mechanistic Lymphoma Research)
Phone or Email: 069-6301-84001 or [e-mail]
Application Deadline: 10.07.2025

We welcome applications from candidates of all genders. Women are currently underrepresented in these positions at Universitätsmedizin Frankfurt. Therefore, applications from women are especially encouraged. Applicants with severe disabilities will be given preferential consideration in cases of equal personal and professional qualifications.