Master Thesis in Cancer Research – Department of Medicine 2, Hematology and Oncology

Universitätsklinikum Frankfurt; Frankfurt; Vor Ort; EUR 40.000 - 60.000; Vollzeit

Zusammenfassung

Le département de médecine 2 à l'Universitätsklinikum Frankfurt recrute un étudiant en master pour rejoindre son programme de recherche sur les vulnérabilités cancéreuses. Vous participerez à des projets passionnants autour de la biologie cellulaire et moléculaire en oncologie, avec un encadrement académique de qualité. Une opportunité enrichissante au sein d'une équipe internationale, axée sur la recherche de pointe.

Leistungen

Environnement de travail international

Soutien à l'éducation scientifique

Accès à des installations modernes

Qualifikationen

• Étudiant en master dans un domaine pertinent.
• Expérience souhaitée dans les techniques de laboratoire.
• Connaissance de la recherche en oncologie est un avantage.

Aufgaben

• Effectuer des tâches en biologie moléculaire et biotechnologie.
• Modifier génétiquement des lignées cellulaires.
• Analyser des données et présenter des résultats scientifiques.

Kenntnisse

Enthousiasme pour la recherche biomédicale

Motivation pour les travaux expérimentaux

Capacité à travailler en équipe

Compétences en biologie cellulaire et moléculaire

Connaissances de base en MS-Office

Anglais courant

Ausbildung

Programme de master en biologie, biochimie ou discipline connexe

Tools

Techniques de biologie moléculaire

CRISPR-Cas9

MS-Office

Jobbeschreibung

...you're in the middle of it

TheDepartment of Medicine 2, Hematology/ Oncologyat theGoethe UniversityHospital Frankfurtoffers the entire spectrum of diagnostics and therapy of malignant diseases as well as a research program focusing on several cancer entities. The research laboratory of Professor Thomas Oellerich is part of the Frankfurt Cancer Institute and focuses on oncogenic signaling and therapy resistance mechanisms in lymphoma and acute myeloid leukemia.
The lab is furthermore funded by the German Cancer Consortium (DKTK), which was founded in 2012 as one of the six German Centers of Excellence for Health Research (DZG). DKTK aims at bringing promising results from cancer research faster into clinical development and patient care. In the DKTK more than 20 academic research institutions and university hospitals at seven partner sites cooperate with each other and the German Cancer Research Center (DKFZ) in Heidelberg as the core center (https://dktk.dkfz.de/standorte/frankfurt-mainz).

Your Role:

The project focuses on deciphering a novel cancer vulnerability in Lymphoma. The gene of interest is involved in ubiquitin-like protein (UBL) signaling that seems to influence B-cell development.

• Molecular biology tasks include Western Blotting, cell culture, DNA-damage and replication assays, flow cytometry and image-based assays.
• Genetic modification of cancer cell lines utilizing CRISPR-Cas9 and shRNA-mediated knockdowns
• State-of-the-Art advanced techniques such as proximity-labeling, MassSpec proteomics, RNAseq
• Data analysis, figure generation and scientific presentations

... your skills are what we're looking for

• Enrolled in a university master program in biology, biochemistry or a related discipline
• Enthusiasm and fascination for biomedical research, oncology, cell and molecular biology
• High motivation for experimental lab work
• Experiences in cell and molecular biological as well as biochemical lab techniques might be of advantage
• Ability to work in a team, sense of responsibility and proactivity
• Basic knowledge in MS-Office (Word, Excel)
• Fluent in English
• Due to legal regulations, valid proof of measles immunity / measles vaccination is required

... you'll be offered a lot

• Collective labour agreement TV GU
• International and cosmopolitan working environment
• Excellent tandem supervision by a PhD student (Ria Mainkar) and a Team Leader (Dr. Ramesh K Krishnan)
• Scientific education including the management of scientific literature, a bi-weekly journal club, good scientific presentation and publication practice
• Uniklinik-Campus, Mensa, Cafés
• Insights: Instagram, YouTube, LinkedIn
• FAQ´s for new employees

It's time to join our team!

Contact: Dr. Niklas Dienstbier (Team Lead - Mechanistic Lymphoma Research)
Phone or Email: 069-6301-84001 or [e-mail]
Application Deadline: 10.07.2025

We welcome applications from candidates of all genders. Women are currently underrepresented in these positions at Universitätsmedizin Frankfurt. Therefore, applications from women are especially encouraged. Applicants with severe disabilities will be given preferential consideration in cases of equal personal and professional qualifications.