Master Thesis - Development of a Simulator for Neuro-monitoring Use Cases

Brainlab; Waldkirch; On-site; EUR 10,000 - 13,000; Part time

Benefits offered by this job

Flexible working hours

International team environment

Internal fitness program

Training and career opportunities

Job summary

Brainlab is offering a Master Thesis position in Waldkirch to develop a functional simulator for intraoperative neuromonitoring. You will explore neurophysiological signals, analyze influencing factors, and design a hardware-software test system with a configurable interface for signal parameters.

The project emphasizes literature review, hardware selection (sources, microcontrollers, filters, amplifiers), and validation against neuromonitoring systems, aiming to derive a near-production concept.

Qualifications

• Interest in biosignal processing, electronics, and physiological processes.
• Basic knowledge of embedded systems and/or signal processing is a plus.

Responsibilities

• Develop a functional prototype of a simulator for neurophysiological signals for intraoperative neuromonitoring (IONM).
• Design and construction of a test system, including hardware and software.
• Develop a configurable user interface for controlling signal parameters (amplitude, frequency, latency, interference).
• Validate the solution with existing neuromonitoring systems.
• Document, analyze and evaluate results and derive a near-production development concept.

Skills

Biosignal processing

Embedded systems

Signal processing

Analytical thinking

Research and development

Education

Master’s degree in electrical engineering, medical engineering, biomedical engineering, physics, or related field

Job description

Master Thesis - Development of a Simulator for Neuro-monitoring Use Cases

• Part-time
• Department: R&D Software

Dr. Langer Medical GmbH, based in Waldkirch, Germany, which has been part of Brainlab SE in Munich since 2022, has specialized in the development and marketing of highly innovative medical technology for intraoperative neuromonitoring and neurostimulation for more than 25 years. Our products are groundbreaking in design and handling and form the basis for our worldwide growth. It is therefore no coincidence that the products from Dr. Langer Medical as well as the company itself have been honored several times in the past with various prizes and awards.

As part of your master’s thesis, you will develop a functional prototype of a simulator for neurophysiological signals for use in intraoperative neuromonitoring (IONM). Your responsibilities will include, in particular:

• Conducting a comprehensive literature review on the neurophysiological fundamentals and signal characteristics (EMG, evoked potentials)
• Analyzing relevant influencing factors such as anesthesia, muscle relaxants, and technical interference
• Developing a technical concept for generating realistic bioelectrical signals
• Selecting and designing suitable hardware components (e.g., signal sources, microcontrollers, filters, amplifiers)
• Design and construction of a test system, including hardware and software
• Development of a configurable user interface for controlling signal parameters (amplitude, frequency, latency, interference variables)
• Simulation of clinically relevant influencing factors such as electrical interference signals or pharmacological effects
• Validation of the developed solution with existing neuromonitoring systems
• Documentation, analysis, and evaluation of the results
• Derivation of a concept for further development into a near-production product

• Master’s degree in electrical engineering, medical engineering, biomedical engineering, physics, or a related field
• Interest in biosignal processing, electronics, and physiological processes
• Basic knowledge of embedded systems and/or signal processing is a plus
• Ability to work in a structured and independent manner
• Analytical thinking skills and an interest in research and development

• Working environment: A mutually-supportive, international team
• Practical experience: Opportunity to build career experience in an exciting international company with a lasting impact on medical technology based in Waldkirch (top 100 innovator and employer of the future 2022)
• Working conditions: Flexible working hours
• Fitness: Internal company fitness program
• Personal development:Training and career opportunities offered by Brainlab SE