Master's Thesis – Nanocarrier Development for Immune Cell Targeting (f/m/x)

Helmholtz Munich; München; Vor Ort; EUR 13.392 - 20.088; Vollzeit

Zusammenfassung

Helmholtz Munich’s Institute for Intelligent Biotechnologies (iBIO) invites a motivated enrolled Master’s student in Bioengineering, Biochemistry, Biomedical Sciences, or related discipline to join a cutting-edge nanotechnology and drug delivery project.

You will design and evaluate targeting ligands, perform LNP formulation, characterize nanocarriers, and participate in library screening and tissue imaging with interdisciplinary colleagues.

Qualifikationen

• Enrolled Master’s student in Bioengineering, Biochemistry, Biomedical Sciences, or related discipline.
• Solid laboratory experience.
• Interest in nanotechnology and drug delivery.
• Structured, independent working style with ability to work collaboratively in an interdisciplinary team.

Aufgaben

• Design and evaluation of targeting ligands (e.g., peptides)
• LNP formulation and ligand conjugation
• Physicochemical characterization of nanocarriers
• Library screening using barcoding approaches
• Performance analysis in tissue-cleared mice using light-sheet microscopy
• Quantitative assessment of immune organ and cell-type targeting

Kenntnisse

Solid laboratory experience

Interest in nanotechnology and drug‑to

Ausbildung

Master's student in Bioengineering/Biochemistry/Biomedical Sciences

Tools

Primer design

PCR

Sequencing

Jobbeschreibung

At Helmholtz Munich, we develop groundbreaking solutions for a healthier society in a rapidly changing world. We believe that diverse perspectives drive innovation. Through strong partnerships, we accelerate the transfer of new ideas from the lab to real-life applications, improving lives.

At the Institute for Intelligent Biotechnologies (iBIO) our major goal is to accelerate biomedical research by developing and combining enabling technologies. Our major research fields are AI-based organ mapping, Tissue engineering and Precision medicine in cancer treatments. Sophisticated technologies such as 3D tissue imaging, molecular profiling are combined with AI tools to decode the complexity of tissues and shed light into cancer biology.

Our interdisciplinary team — comprising biologists, engineers, computer scientists, and medical researchers — develops next-generation computational models to interpret complex biomedical data across multiple scales. Our innovations in tissue clearing, 3D microscopy, and AI-driven pathology have been featured in leading journals (Nature Methods, Nature Neuroscience, Cell, Nature Biotechnology) and major media (The New York Times, Wall Street Journal, Süddeutsche Zeitung).

Responsibilities

• Design and evaluation of targeting ligands (e.g., peptides)
• LNP formulation and ligand conjugation
• Physicochemical characterization of nanocarriers
• Library screening using barcoding approaches
• Performance analysis in tissue-cleared mice using light-sheet microscopy
• Quantitative assessment of immune organ and cell-type targeting

Requirements

• Enrolled Master’s student in Bioengineering, Biochemistry, Biomedical Sciences, or related discipline
• Solid laboratory experience
• Interest in nanotechnology and drug delivery
• Structured, independent working style with ability to work collaboratively in an interdisciplinary team

Desirable Qualifications

• Experience with peptide design or in silico tools
• Experience in primer design, PCR, sequencing

We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. Qualified applicants with physical disabilities will be given preference.

If you have any questions, feel free to contact Stefanie Reitinger, [e-mail], who will be happy to help.