Research Associate - Functional Genomics

German Cancer Research Center in the Helmholtz Association (DKFZ); Deutschland; Vor Ort; EUR 45.000 - 65.000; Vollzeit

Zusammenfassung

The German Cancer Research Center is seeking a Research Associate in Functional Genomics to support projects on bone and soft-tissue sarcomas. The role involves lab management, data analysis, and collaboration with team members to advance research in cancer treatment. Candidates should have a Master's or PhD and experience in molecular biology and cell culture.

Leistungen

30 days of vacation per year

Flexible working hours

Remuneration according to TV-L

Company pension scheme

Sustainable travel to work

Corporate Health Management Program

Qualifikationen

• Master's or PhD in relevant field.
• Extensive experience with cell culture and molecular biology methods.
• Competence in programming languages (R, Python) is beneficial.

Aufgaben

• Support various lab projects and manage lab coordination.
• Analyze next-generation sequencing data and perform CRISPR/Cas9 screens.
• Document and present results in meetings and conferences.

Kenntnisse

Cell culture

Molecular biology methods

Programming languages (R, Python)

Organizational skills

Team collaboration

English proficiency

Ausbildung

Master of Science or PhD

Jobbeschreibung

“Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

The Precision Sarcoma Researchgroup at the German Cancer Research Center and the National Center for Tumor Diseases Heidelberg (Head: Dr. Priya Chudasama) is seeking for the next possible date a

Research Associate – Functional Genomics

Reference number: 2025-0139

We are looking for a qualified and motivated research associate to expand our international, inclusive and ambitious team to contribute to projects focused on better understanding of rare cancers called bone and soft-tissue sarcoma, a large and heterogeneous group of aggressive tumors affecting all age groups with urgent unmet medical need. Our group uses computational and functional genomics approaches to characterize tumor specimens and cell models to identify mechanisms of sarcomagenesis and new biology-guided treatments. More details on the team and specific on-going projects could be found here:https://www.dkfz.de/en/precision-sarcoma-research

Your Tasks:

The successful candidate will flexibly support different on-going projects in the lab in close collaboration with team members and external collaborators, and take on lab management and coordination duties. The methods and general responsibilities include, but are not limited to:

• Analysis of next-generation sequencing data derived from human sarcoma samplesto identify genome, transcriptomeand methylome alterations, if bioinformatics expertise is available
• CRISPR/Cas9 screens
• Molecular biology methods (sample preparation, cloning, sequencing, mutagenesis, PCR)
• Routine cell culture methods (culture of cell lines, production of lentiviruses, transduction of cell lines, different assays for hallmarks of cancer)
• Flow cytometry and cell sorting
• Protein detection (western blotting, immunoprecipitation, immunofluorescence)
• Comprehensive documentation and presentation of results in lab meetings and conferences
• Independent planning and coordination of project, analysis, and interpretation of results, establishment of new methods, supervision of new lab members
• Manage key communication with collaborators, third-party service providers, and other internal departments
• Support laboratory management (ordering of reagents and consumables, maintaining inventories and lab databases, shipments)

Your Profile:

• Master of Science, PhD or equivalent degree
• Extensive experience with cell culture and molecular biologymethods
• Competence and experience in programming languages (R, Python), experience with analysis of next-generation sequencing data will be a plus
• Exceptional organizational and time management skills, willingness to support different projects in parallel, as well as to move between sites for use of different technology platforms
• True team player,high level of intrinsic motivation, reliability
• Excellent command of written and spoken English and effective oral and written presentation skills, German language skills would be helpful but not a must

Interested candidates should send applications with full CV with publications, references and cover letter explicitly mentioning the date of availability. Incomplete applications will not be considered. In case of urgent questions, please write an email to [e-mail]. Please apply exclusively via the application portal.

We Offer Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level 30 days of vacation per year Flexible working hours Remuneration according to TV-L incl. company pension scheme and capital-forming benefits Possibility of part-time work Family-friendly working environment Sustainable travel to work: subsidized Germany job ticket Unleash your full potential: targeted offers for your personal development promote your talents Our Corporate Health Management Program offers a holistic approach to your well-being

Contact:
Dr.PriyaChudasama
Telefon: [phone]

The position is initially limited to 1 year with the possibility of prolongation.

Are you interested?

Then become part of the DKFZ and join us in contributing to a life without cancer!

Apply now

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Notice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

Share this job!

Deutsches Krebsforschungszentrum | Im Neuenheimer Feld 280 | 69120 Heidelberg | www.dkfz.de