Senior Director, Pharmacometrics

TN Germany; Berlin; Vor Ort; EUR 80.000 - 120.000; Vollzeit

Zusammenfassung

An innovative company in the pharmaceutical sector seeks a Senior Director of Pharmacometrics in Berlin. This role involves leading quantitative decision-making in drug development, utilizing advanced modeling techniques to enhance patient outcomes and accelerate regulatory approvals. The ideal candidate will have a strong background in pharmacometrics and a passion for strategic drug development. Join a dynamic team that values creativity and continuous development, and make a meaningful impact on the future of medicine. This is a unique opportunity to work with a variety of therapeutic areas and contribute to groundbreaking projects.

Qualifikationen

• PhD, MD, or PharmD in relevant fields required.
• Experience in pharmacometrics and clinical environments preferred.
• Strong quantitative skills in modeling and analysis.

Aufgaben

• Support quantitative decision-making in drug development.
• Engage in pharmacometric modeling on client projects.
• Conduct quality control on model codes and reports.

Kenntnisse

Pharmacometrics

Population PK Modeling

PK/PD Modeling

Statistical Analysis

Modeling Software (NONMEM, R)

Ausbildung

PhD in Bioengineering

MD in Pharmaceutical Sciences

PharmD

Tools

NONMEM

R

Jobbeschreibung

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Senior Director, Pharmacometrics, Berlin

Client: Certara

Location: Berlin, Germany

Job Category: Other

EU work permit required: Yes

Job Reference: 7135a49af8df

Job Views: 1

Posted: 09.05.2025

Expiry Date: 23.06.2025

Job Description:

Overview

Certara is a growing company that provides a dynamic and exciting place to work. Our purpose is to assist in accelerating the development of meaningful medicines that make an impact on our society and the people that need them most. Innovation and creativity are highly valued, and everyone is given the opportunity for training and continuous development. Our portfolio spans the discovery, preclinical, clinical, and post-marketing phases of drug development, working with 1,200 commercial companies, 250 academic institutions, and numerous regulatory agencies.

In the past 6 years, over 90% of companies that received new drug approvals by the FDA used our software or services. Our integrated and proprietary end-to-end platform with biosimulation, regulatory science, and market access solutions, combined with our strong team of scientists and subject matter experts, enables our clients to have:

• Informed decision-making & reduced clinical trial burden
• Higher R&D productivity
• Improved patient outcomes & increased patient access to medicines
• Accelerated regulatory approval

Responsibilities

Our Pharmacometricians are responsible for supporting quantitative decision-making in drug development through the development and application of population PK, PK/PD, exposure-response, and other models. Qualified candidates will have the ability to work on various therapeutic indications and data types and must be experts in applied Population PK, PK/PD, and/or exposure-response modelling and simulation to support drug development.

We are looking for Pharmacometricians that want to:

• Deepen their strategic drug development expertise and experience informing drug development decisions.
• Hone their pharmacometric techniques with fit-for-purpose modelling approaches leveraging e.g., model-based meta-analysis, target-mediated drug disposition models, and E-R trial simulations.
• Broaden their drug development expertise by working with a variety of companies, molecular modalities, and therapeutic areas.
• Develop their consulting career path by recognizing and seeking opportunities that match their ambitions and personal interests.
• Support projects for Certara’s clients by working in teams with other associates, senior expert modelers, and drug development consultants.
• Engage in hands-on pharmacometric modeling on client projects as a billable consultant.
• Conduct quality control activities on model codes and reports.
• May lead or coordinate company initiatives (e.g., IT, methodology, efficiency, automation, quality).
• May act as the primary point of contact for clients and collaborate with a senior consultant to grow the business to match their interests.

Qualifications

• PhD, MD, PharmD in Bioengineering, Pharmaceutical Sciences, Pharmacology, Statistics, Applied Mathematics, Engineering, Medicine, or a related field.
• Industry consulting experience (may be combined with academic research) working in R&D, pre-clinical, and clinical environments.
• Solid experience in pharmacometrics, clinical pharmacology, pharmacokinetics, or a related discipline in a project team setting is preferred, whether in academia or industry.
• Expertise in PK/PD modelling with strong quantitative skills applied to develop models with nonlinear behavior, mechanistic or semi-mechanistic components relating to mechanism of action, tailored to meet specific drug-development questions.
• Proficiency in PK/PD and statistical software (e.g., NONMEM, R).
• Proficient in modeling (e.g., popPK and PK/PD analyses, model-based meta-analysis, dose-response and exposure-response analyses, dataset creation, disease modeling, trial simulation, optimal study designs, strategic decision analyses, economic modeling).
• Experience in moving compounds through the clinical trials process and with various elements of clinical development, trial design, management, and filings is preferred.

Certara bases all employment-related decisions on merit, considering qualifications, skills, achievement, and performance. We treat all applicants and employees equally, regardless of personal characteristics such as race, color, ethnicity, religion, sex, sexual orientation, age, nationality, marital status, pregnancy, physical or mental condition, genetic information, military service, or other protected characteristics.