PhD Candidate (m/f/d): Preclinical Metabolomics

Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V.; Deutschland; Vor Ort; EUR 30.000 - 40.000; Teilzeit

Zusammenfassung

L'Institut Leibniz pour les sciences analytiques recherche un candidat au doctorat en métabolomique préclinique. Le poste implique des recherches sur le stress oxydatif lié au mélanome métastatique, avec une formation et un soutien offerts dans un environnement international. Les candidats doivent avoir un diplôme en biologie ou chimie analytique et une bonne maîtrise de l'anglais.

Leistungen

Formation et développement scientifique

Horaires de travail flexibles

Soutien à la conciliation travail-famille

Promotion de la santé au travail

Qualifikationen

• Diplôme en Biologie, Chimie analytique, Biochimie ou équivalent.
• Expérience pratique avec des spectromètres de masse est un plus.
• Bonne compréhension des outils comme les cultures cellulaires et l'histopathologie.

Aufgaben

• Recherche sur le stress oxydatif dans les ganglions lymphatiques.
• Caractérisation biochimique et histopathologique des cellules tumorales.
• Analyse de données de séquençage et de microscopie.

Kenntnisse

Cell cultures

Histopathology

Microscopy

Chromatography

Data analysis

English communication

Ausbildung

Masters, Diploma or equivalent degree in Biology, Analytical Chemistry, Biochemistry

Tools

Mass spectrometers

Jobbeschreibung

The Leibniz-Institut für Analytische Wissenschaften - ISAS - e. V. develops efficient analytical methods for health research. Thus, it contributes to the improvement of the prevention, early diagnosis, and therapy of diseases like cardiovascular diseases or cancer. Overall, the institute strives to advance precision medicine by combining knowledge from different fields such as biology, chemistry, computer science, medicine, pharmacology, and physics. ISAS is a member of the Leibniz Association and is publicly funded by the Federal Republic of Germany and its federal states.

At our location in Dortmund, we invite applications for a

PhD Candidate (m/f/d): Preclinical Metabolomics

You will be responsible for

• Researching oxidative stress within lymph nodes caused by metastatic melanoma
• Biochemical and histopathological characterization of tumor cells in tissues using chemical and fluorescence staining
• Handling in vivo and in vitro models to test research hypothesis and refine study designs
• Studying lipid alterations of tumorous material by mass spectrometry imaging
• Quantification of corresponding lipids using liquid chromatography mass spectrometry
• Data analysis of sequencing and microscopy data
• Data analysis of mass spectrometry data

Your profile

• Masters, Diploma or equivalent degree in Biology, Analytical Chemistry, Biochemistry or related subjects
• Good understanding of tools such cell cultures, histopathology, microscopy, and/or chromatography
• Hands-on experience with mass spectrometers is a plus
• Excellent English communication and writing skills
• Basic understanding of cancer biology is preferable

We offer

• A clear research topic as well as multifold training and support for PhD students in framework of ISAS and the Leibniz association
• Training and scientific development opportunities in an international environment and an excellent working atmosphere in a very dynamic and professional team
• Extensive state-of-the-art equipment and infrastructure in various analytical methods
• The opportunity to present your data on international conferences and participate in workshops
• A wide range of opportunities for further training and qualifications
• Flexible working times, mobile working and attractive social benefits
• Support in finding balance between work and family life (including finding childcare facilities, advice on caring for relatives) through a family service
• Workplace health promotion and support for participation in TU Dortmund University sports activities

Non-residents who apply for this job will receive help from the institute to find accommodation and to handle authorities. Applications from disabled applicants are welcome. ISAS supports the principle of equal opportunity for all employees and therefore particularly encourages women to apply.

The salary will be according to the German TV-L. The part-time position (65%) is offered for 3,5 years. The position is available immediately. The time limitation of the contract is based on the Wissenschafts-zeitvertragsgesetz (WissZeitVG).

ISAS collects and processes the personal data of its applicants in accordance with European and German legal regulations. Further information on data protection and the processing of personal data can be found at: https://www.isas.de/en/datenschutz.

The closing date for applications is May 27, 2025. Please apply via our applicant portal. If you have any questions (reference number 351_2025), feel free to contact the Human Resources team ([e-mail]). Further information about the institute can be found at: https://www.isas.de/en