1 Postdoc (m/w/d) / Abteilung Experimentelle Diabetologie

Dife

Potsdam

Hybrid

EUR 55,000 - 75,000

Full time

12 days ago

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Benefits offered by this job

TV-L13 remuneration with annual bonus
Company pension scheme
Audit berufundfamilie — family‑orented
Jobticket for public transport
Free parking

Job summary

German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) seeks a Computational Biologist/Bioinformatician to join teams studying how obesity and type 2 diabetes reshape the epigenome. You will work with mouse models and translational validation in humans to identify disease genes and epigenetic changes.

You will perform integrative analyses of multiomics data, develop clear visualizations, and communicate insights to lab scientists and collaborators in an interdisciplinary environment.

Qualifications

  • Master and doctoral degree in Computational Science/Bioinformatics.
  • Strong background in genetics and epigenetics.
  • Experience with multiome data analysis (e.g. Lipidomics, Proteomics, ATAC-seq).
  • Proficiency in programming languages such as R or Python.
  • Excellent communication and ability to work in interdisciplinary teams.

Responsibilities

  • Perform end-to-end data analysis including QC, integration and network inference.
  • Analyze multiome datasets (transcriptomics, epigenomics and related modalities).
  • Apply advanced computational methods for integrative analysis of multi-layer data.
  • Develop clear data visualizations, reports and summaries to communicate results.
  • Collaborate closely with laboratory scientists to translate biological questions into analyses.

Skills

Computational Biology
Bioinformatics
R/Python
Multi-omics analysis
Data integration
Interdisciplinary collaboration
English fluency

Education

Master in Computational Science/Bioinformatics
PhD in Computational Science/Bioinformatics

Tools

R
Python

Job description

The German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) is a member of the Leibniz Association. The institute’s mission is to conduct experimental and clinical research in the field of nutrition and health, with the aim of understanding the molecular basis of nutrition-dependent diseases, and of developing new strategies for treatment and prevention.

We are looking for a highly motivated Computational Biologist/Bioinformatician to join our teams, which focus on understanding how obesity and type 2 diabetes reshape the epigenome, with the goal of identifying disease-associated genes and epigenetic alterations. Using lean and obese mouse models and translational validation in humans, we investigate how interventions such as intermittent fasting, endurance training, and bariatric surgery can modulate disease-induced molecular changes.

Tasks
  • Perform end-to-end data analysis, including quality control, data integration and inference of regulatory networks
  • Analyze and interpret multiome datasets (e.g. transcriptomics, epigenomics and related modalities)
  • Apply advanced computational and statistical methods for integrative analysis of multi-layer biological data
  • Develop clear data visualizations, reports and written summaries to communicate results
  • Collaborate closely with laboratory scientists to translate biological questions into computational analyses
Skills and requirements
  • Excellent master and doctoral degree in Computational Science/Bioinformatics
  • Strong background in biological fundamentals, including genetics and epigenetics
  • Experience with multiome data analysis (e. g. Lipidomics, Proteomics, ATAC-seq)
  • Expertise in programming languages such as R or Python
  • Proven experience with advanced computational methods for data integration and interpretation
  • Strong communication skills and ability to work in interdisciplinary teams
  • Fluency in spoken and written English
We offer:
  • Excellent technical equipment, a wide range of experimental methods and a dynamic and interactive research environment
  • Remuneration according to TV-L, level 13, plus annual special payment and company pension scheme
  • Family-friendly working conditions (certificate “audit berufundfamilie”)
  • Supporting of mobility with a jobticket for using the public transport
  • Easy accessibility by public transport or car (including free parking)
  • 30 days of vacation
  • Participation in the benefits program for employees („Corporate Benefits“)

The advertised position is available for 1 year.

We promote the employment of people with severe disabilities and are committed to equal opportunities for them. Applicants with severe disabilities will be given preferential consideration if they have the same qualifications.

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