RNAi Formulations Scientist - Contract, High-Throughput

Proclinical; Schweiz; On-site; CHF 40,000 - 44,000; Full time

Job summary

Proclinical is seeking an Associate Research Scientist for RNAi Formulations to perform hands-on formulation development and biophysical characterization for preclinical RNAi and oligonucleotide therapeutics in a fast-paced research setting.

The role requires MS or PhD with relevant experience; proficiency in analytical testing, data analysis, and DOE-based optimization is valued, along with strong communication across disciplines.

Qualifications

• MS or PhD in pharmaceutical sciences, formulation sciences, chemical engineering, biophysics, analytical chemistry, oligonucleotide delivery, or related discipline.
• Hands-on oligonucleotide or antibodies/proteins formulation and characterization experience preferred.
• Experience developing or running analytical methods for solubility, viscosity, osmolality, aggregation, stability for complex formulations.

Responsibilities

• Support development and characterization of preclinical RNAi and oligonucleotide formulations across projects.
• Execute hands-on formulation prep, biophysical characterization, analytical testing, and data analysis.
• Establish and run screening assays for oligonucleotides in early discovery, including solubility and stability assessments.
• Contribute to high-throughput and DOE-based formulation optimization.
• Support long-term storage and stability evaluations for RNAi conjugates.
• Maintain accurate experimental documentation and communicate findings through reports and presentations.
• Collaborate with internal and external partners to support project deliverables.
• Identify gaps and propose practical improvements to workflows.
• Thrive in a multidisciplinary, fast-paced research environment.

Skills

RNAi formulation

DoE optimization

Automation & HTS

Analytical testing & data analysis

Scientific communication

Education

MS or PhD in related field

Job description

Proclinical is seeking an Associate Research Scientist for RNAi Formulations to perform hands-on formulation development and biophysical characterization for preclinical RNAi and oligonucleotide therapeutics in a fast-paced research setting.

The role requires MS or PhD with relevant experience; proficiency in analytical testing, data analysis, and DOE-based optimization is valued, along with strong communication across disciplines.