Oligonucleotide Synthesis Intern — Hands-On Lab Experience

3M HEALTHCARE; Basel; On-site; CHF 17,000 - 23,000; Full time

Job summary

Roche in Basel invites you to join the Preclinical Chemistry, Manufacturing, and Controls (pCMC) team within pRED for an internship. You will explore either oligonucleotide synthesis and purification or advanced LC-MS analytics, gaining hands-on laboratory experience and collaboration across a dynamic, science-driven environment.

The position emphasizes curiosity, responsibility, and teamwork, with opportunities to contribute to innovative drug development while developing critical lab skills

Qualifications

• BSc or MSc student or recent graduate in Chemistry or Biochemistry, within 12 months of start date.
• Hands-on laboratory experience required.
• Experience with oligonucleotide chemistry or LC-MS analytics is desirable.
• Excellent written and verbal communication in English.
• Strong organizational skills and willingness to learn.

Responsibilities

• Option 1: contribute to oligonucleotide synthesis, purification, and analysis using state-of-the-art chromatography; scale up to multi-gram materials.
• Option 2: perform state-of-the-art LC-MS analysis of complex oligonucleotides; develop analytical methods for synthesis and production; conduct stability and hold-time studies.

Skills

Oligonucleotide chemistry

LC-MS analytics

Synthesis purification

English communication

Education

BSc or MSc in Chemistry or Biochemistry

Tools

LC-MS instruments

Solid phase synthesis equipment

Job description

Roche in Basel invites you to join the Preclinical Chemistry, Manufacturing, and Controls (pCMC) team within pRED for an internship. You will explore either oligonucleotide synthesis and purification or advanced LC-MS analytics, gaining hands-on laboratory experience and collaboration across a dynamic, science-driven environment.

The position emphasizes curiosity, responsibility, and teamwork, with opportunities to contribute to innovative drug development while developing critical lab skills