Lead siRNA Design Scientist for Therapeutics

Roche; Basel; Vor Ort; CHF 120.000 - 160.000; Vollzeit

Zusammenfassung

Roche is looking for a siRNA Design Principal Scientist to lead the therapeutic siRNA candidates design and optimization process across various disease targets. This role requires a Ph.D. with over 5 years of industry experience in siRNA therapeutic design, along with strong skills in molecular biology and bioinformatics.

The ideal candidate will have a proven track record in applying chemical modification patterns to enhance therapeutic profiles and excellent communication skills to translate complex scientific concepts for diverse audiences.

Qualifikationen

• Ph.D. with 5+ years of experience in siRNA/RNAi therapeutic design.
• Deep understanding of RNAi mechanisms and siRNA profiling.
• Proven track record enhancing therapeutic profiles through chemical modifications.

Aufgaben

• Lead drug design strategy for oligonucleotides, focusing on siRNAs.
• Guide projects to ensure design decisions meet clinical requirements.
• Invent chemical modification patterns and selection strategies for siRNAs.

Kenntnisse

Molecular Biology

Bioinformatics

SiRNA Therapeutic Design

Communication Skills

Chemical Modification Patterns

AI Collaboration

Ausbildung

Ph.D. in Molecular Biology or related field

Tools

Command-line utilities

Scripting languages

Jobbeschreibung

Roche is looking for a siRNA Design Principal Scientist to lead the therapeutic siRNA candidates design and optimization process across various disease targets. This role requires a Ph.D. with over 5 years of industry experience in siRNA therapeutic design, along with strong skills in molecular biology and bioinformatics.

The ideal candidate will have a proven track record in applying chemical modification patterns to enhance therapeutic profiles and excellent communication skills to translate complex scientific concepts for diverse audiences.