Formulation Scientist

Dr Reddy's Laboratories Ltd - Sandbox; Genf; Vor Ort; CHF 120.000 - 160.000; Vollzeit

Zusammenfassung

A leading pharmaceutical company in Switzerland is seeking a highly skilled professional for their R&D department. The role involves developing and characterizing prototype formulations for small molecules and conducting analytical assessments. Candidates need a Master's degree in a relevant science field and a minimum of ten years' experience in the pharmaceutical industry, specifically in R&D. Knowledge of FDA guidelines and experience with injectable products are essential for success in this position.

Qualifikationen

• Minimum ten years of experience in pharmaceutical industry in R&D.
• Experienced with development of injectable (generic) products.
• Capable of applying FDA guidelines, ICH, USP & EP chapters.

Aufgaben

• Development of prototype formulations for pharmaceutical small molecules.
• Routine preparation and characterization of formulation solutions.
• Assessment of chemical and physical properties of small molecules.

Kenntnisse

Analytical thinking

Problem-solving skills

Communication skills

Interpersonal skills

Organizational skills

Ausbildung

Masters degree in relevant science field

Tools

MS Office (Word, Excel, Projects, PowerPoint)

Jobbeschreibung

Dr. Reddy’s Laboratories Ltd. is a leading multinational pharmaceutical company based across global locations. Each of our 24,000 plus employees comes to work every day for one collective purpose: to accelerate access to affordable and innovative medicines because Good Health Can’t Wait.

We started in 1984 with a modest investment, 20 employees and a bold vision. Today, we have research and development centres, manufacturing facilities or a commercial presence in 66 countries.

For nearly four decades, we have stood for access, affordability and innovation based on the bedrock of deep science, progressive people practices and robust corporate governance. As the pharmaceutical industry evolves and undergoes disruption, we see an opportunity – to strengthen our core further (the next steps) and to build the future (the new bets).

‘The Next and the New’ is how we aim to continue to be the partner of choice – purpose-driven, future-ready and sustainable. Our aim is to reach over 1.5 Bn+ patients across the world by 2030 by growing our core businesses and building for the future with sustainability at the core of our purpose and strategy. Sustainability for us means operating in a manner that respects people, planet and purpose – helping us conserve precious resources, serve our patients, create value for stakeholders, give back to society, fulfil our potential and maintain our integrity and transparency

Dr Reddy’s maintains a work environment, free from discrimination and is an equal opportunity employer. We are committed to employ & nurture all qualified diverse workforce without regard to race, colour religion, nationality, sex, age, disability status, genetics, sexual orientation, gender expression, citizenship or any other characteristic or classification protected by applicable law(s) of the country we operate in. We treasure every talent, and recognize merit and diversity in our organization.

Job Description

• Development of prototype formulations (solutions, suspensions, dispersions, etc.) for pharmaceutical small molecules for exploratory studies for in vivo models. This activity includes development and characterization of both oral and parenteral dosage forms on small scale with small amounts of material (mg) on rapid timelines.
• Routine preparation and characterization of solution and suspension formulations for use in preclinical efficacy, pharmacokinetic and toxicology studies with novel small molecule therapeutics and derivatives using High performance liquid chromatography (HPLC)
• Measurement of key active compound and formulation properties (such as crystallinity, solubility, dissolution, permeation, stability, self-association, etc)
• Assessment of the chemical and physical properties of small molecules
• Assessment of the performance of prototype formulations using in-vitro tests (dissolution, precipitation, etc.).
• Development of detailed protocols for preparation of formulations at other sites, both internal and external and development and use of formulation problem-solving and troubleshooting skills
• Handling and formulation of high potency/OEB5 compounds using an isolator setup.
• Rapid and detailed documentation of experimental procedures and data in electronic laboratory notebooks.
• Shipment of samples to external sites.

Qualifications

• Masters degree in relevant science field, Pharmacy, Pharmaceutical Sciences, Chemical Engineering or related disciplines.
• Proficient in MS Office (Word, Excel, Projects, PowerPoint).
• Organizational and recordkeeping skills.
• Strong analytical thinking, problem solving skills and decision making skills.
• Take initiative, motivated to excel, have a strong technical background, have excellent communication and interpersonal skills.
• A self-starter with a hands-on approach and a can-do attitude.

Experience

• Minimum ten (10) years of experience in pharmaceutical industry in R&D.
• Experienced with development of injectable (generic) products.
• Experience with complex systems, like microparticles, liposomes, injectable gels, emulsions & suspensions.
• Comprehensive understanding of manufacturing technology and equipment used in parenteral manufacturing, such as lyophilization, homogenization, (wet-ball) milling, compounding, dispensing, filling, autoclaving (sterilization), sterile filtration
• Capable of applying FDA guidelines, ICH, USP & EP chapters.
• Deep understanding in polymer and/or liposomal chemistry.