Scientist Pharmaceutical and Processing Development (2 year fixed term contract)

Roche; Basel; Vor Ort; CHF 120.000 - 160.000; Vollzeit

Zusammenfassung

Roche in Basel, Switzerland seeks a Scientist in Pharmaceutical Development to drive end-to-end parenteral formulation development, from liquid to lyophilized forms, and to establish scalable manufacturing processes for clinical and commercial transfer.

You will lead cross-functional teams, contribute to regulatory submissions (BLA/MAA/NDA), and collaborate with Postdocs and Scientists to test new modalities, including oligonucleotides, within a dynamic and collaborative environment.

Qualifikationen

• Ph.D. or master's in chemistry, chemical/process engineering or related fields.
• Minimum of 2 years of professional experience in formulation and process development for parenteral dosage forms.
• Experience in oligonucleotides is a plus.

Aufgaben

• Lead the end-to-end development of parenteral formulations—including liquid and lyophilized dosage forms—and establish robust manufacturing processes from scale-up and characterization to commercial transfer.
• Represent Pharmaceutical Development as a project leader in global CMC and cross-functional teams, providing critical technical expertise and strategic input for regulatory submissions (BLA/MAA/NDA) throughout all clinical stages.
• Actively apply creative, open-minded approaches to overcome unfavorable molecular properties. Serve as a key lab partner to Postdocs and Scientists to test and validate exploratory formulation concepts and new therapeutic modalities.
• Manage and support analytical method scouting, analytical understanding and implementation capabilities in our routine.

Ausbildung

Ph.D. or master degree in chemistry, chemical/process engineering or related fields

Jobbeschreibung

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

As a Scientist in Pharmaceutical Development, you are part of the Department “Pharmaceutical Development” in Pharma Technical Development (PTD) in Basel, Switzerland. The department Pharmaceutical Development is responsible for the development of parenteral drug products (Synthetic molecules and Biologics) from Phase 1 through market Launch. Activities encompass formulation and manufacturing process development for parenteral drug products for all clinical stages and the market launch, the transfer of product and process to commercial manufacturing sites, commercial product support and line extension development.

You will balance technical rigor in formulation and process development with an exploratory mindset, driving innovation in parenteral modalities, including Oligonucleotides and complex synthetic molecules.

The Opportunity

• Lead the end-to-end development of parenteral formulations—including liquid and lyophilized dosage forms—and establish robust manufacturing processes from scale-up and characterization to commercial transfer
• Represent Pharmaceutical Development as a project leader in global CMC and cross-functional teams, providing critical technical expertise and strategic input for regulatory submissions (BLA/MAA/NDA) throughout all clinical stages
• Actively apply creative, open-minded approaches to overcome unfavorable molecular properties. Serve as a key lab partner to Postdocs and Scientists to test and validate exploratory formulation concepts and new therapeutic modalities.
• Manage and support analytical method scouting, analytical understanding and implementation capabilities in our routine

Who you are

• You hold a Ph.D. or master degree in chemistry, chemical/process engineering or related fields and bring a minimum of 2 years of professional experience (industry) in formulation and process development DP manufacturing related fields of parenteral dosage forms
• Eagerness to Learn & Grow: Strong intrinsic motivation to master new therapeutic modalities, specifically building a deep technical footprint in Oligonucleotide formulation and analytical-formulation loops
• Technical Agility & Curiosity: Comfort in or a strong motivation to acquire knowledge and advance in unfamiliar fields, particularly digital domains. A natural inclination to challenge the status quo and show curiosity
• Collaboration & Communication: Outstanding team player with highly developed interpersonal skills. Thrives in a matrixed environment where resources, ideas, and lab spaces are shared globally to deliver a high-stakes portfolio
• Experience in oligonucleotides is a plus

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.