Scientist Pharmaceutical and Processing Development (2 year fixed term contract)

F. Hoffmann-La Roche AG; Basel; Vor Ort; CHF 110.000 - 160.000; Vollzeit

Zusammenfassung

Roche in Basel is seeking a Scientist in Pharmaceutical Development to lead end-to-end parenteral formulation and process development, from early-stage work to transfer to manufacturing. You will collaborate across global teams to drive regulatory submissions and product transfers.

The ideal candidate holds a PhD or Master in chemistry/related field with 2+ years of industry experience in parenteral DP formulation, and demonstrates curiosity for new modalities such as oligonucleotides.

Qualifikationen

• PhD or Master in chemistry or related field with 2+ years in parenteral DP formulation.
• Strong motivation to learn new modalities such as oligonucleotides.
• Excellent collaboration in matrixed global teams.

Aufgaben

• Lead end-to-end development of parenteral formulations, liquid and lyophilized.
• Establish robust manufacturing processes from scale-up to commercial transfer.
• Represent Pharmaceutical Development as a project leader in global CMC and cross-functional teams.
• Support analytical method scouting and implementation capabilities.

Kenntnisse

Formulation development

Process development

Cross-functional collaboration

Analytical thinking

Ausbildung

PhD or Master in Chemistry/Chemical Engineering

Jobbeschreibung

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

As a Scientist in Pharmaceutical Development, you are part of the Department "Pharmaceutical Development" in Pharma Technical Development (PTD) in Basel, Switzerland. The department Pharmaceutical Development is responsible for the development of parenteral drug products (Synthetic molecules and Biologics) from Phase 1 through market Launch. Activities encompass formulation and manufacturing process development for parenteral drug products for all clinical stages and the market launch, the transfer of product and process to commercial manufacturing sites, commercial product support and line extension development.

The Opportunity

You will balance technical rigor in formulation and process development with an exploratory mindset, driving innovation in parenteral modalities, including Oligonucleotides and complex synthetic molecules. Lead the end-to-end development of parenteral formulations - liquid and lyophilized dosage forms - and establish robust manufacturing processes from scale-up and characterization to commercial transfer. Represent Pharmaceutical Development as a project leader in global CMC and cross-functional teams, providing critical technical expertise and strategic input for regulatory submissions (BLA/MAA/NDA) throughout all clinical stages. Actively apply creative, open-minded approaches to overcome unfavorable molecular properties. Serve as a key lab partner to Postdocs and Scientists to test and validate exploratory formulation concepts and new therapeutic modalities. Manage and support analytical method scouting, analytical understanding and implementation capabilities in our routine.

Who you are

• You hold a Ph.D. or master degree in chemistry, chemical/process engineering or related fields and bring a minimum of 2 years of professional experience (industry) in formulation and process development DP manufacturing related fields of parenteral dosage forms.
• Eagerness to Learn & Grow: Strong intrinsic motivation to master new therapeutic modalities, specifically building a deep technical footprint in Oligonucleotide formulation and analytical-formulation loops.
• Technical Agility & Curiosity: Comfort in or a strong motivation to acquire knowledge and advance in unfamiliar fields, particularly digital domains. A natural inclination to challenge the status quo and show curiosity.
• Collaboration & Communication: Outstanding team player with highly developed interpersonal skills. Thrives in a matrixed environment where resources, ideas, and lab spaces are shared globally to deliver a high-stakes portfolio.
• Experience in oligonucleotides is a plus.

Who we are

A healthier future drives us to innovate. Together, more than 100000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer. We believe it’s urgent to deliver medical solutions right now - even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.