Senior Chemist R&D

Siegfried Evionnaz SA; Evionnaz; Vor Ort; CHF 120.000 - 175.000; Vollzeit

Benefits dieser Stelle

Free on-site parking

Health insurance discount

Share purchase plan

CHF child allowance

Learning opportunities

REKA checks

Pension plan

On-site fitness classes

Swibeco benefits platform

Additional vacation options

Zusammenfassung

Siegfried Evionnaz SA is seeking a Senior Chemist R&D to develop and optimize robust chemical processes for clinical and commercial pharmaceutical products. You will lead cross-functional activities, drive technology transfer from lab to pilot and commercial manufacturing, and mentor junior scientists in a multidisciplinary environment.

You will apply DoE, QbD and PAT methodologies, ensure GMP compliance, and collaborate with Production, QA, Regulatory, and Engineering teams to deliver scalable,

Qualifikationen

• PhD or MSc in Organic Chemistry, Process Chemistry or a related scientific discipline.
• 5+ years of pharmaceutical process development experience.
• Strong expertise in synthetic organic chemistry, reaction mechanisms, process optimization and scale-up.
• Knowledge of DoE, QbD, PAT and statistical data analysis.
• Experience supporting technology transfer from lab to pilot or commercial manufacturing.
• Solid understanding of GMP requirements and ICH guidelines.
• Excellent problem-solving and scientific reasoning.
• Strong communication and stakeholder management abilities, including customer interactions.
• Ability to manage multiple priorities while maintaining high scientific standards.
• Fluency in English and French.

Aufgaben

• Leading development, optimization, and troubleshooting of chemical manufacturing processes.
• Supporting process scale-up and technology transfer from lab to pilot plant and commercial manufacturing.
• Driving continuous improvement to increase process robustness, efficiency, quality and sustainability.
• Applying DoE, QbD, PAT and data analysis to accelerate process understanding.
• Acting as technical lead for customer projects during meetings and discussions.
• Collaborating with cross-functional teams including Production, QA, Regulatory, Engineering and HSE.
• Preparing development reports, risk assessments, tech transfer packages and regulatory documents.
• Identifying innovative technologies to strengthen process development capabilities.
• Mentoring junior scientists and sharing knowledge across the organization.
• Contributing to strategic development of Process Development through innovation and operational excellence.

Kenntnisse

Organic chemistry

DoE

QbD

PAT

Process optimization

Scale-up

Communication

Stakeholder management

English and French

Ausbildung

PhD or MSc in Organic Chemistry/Process Chemistry

Jobbeschreibung

\"Expect to grow\", personally and professionally: At Siegfried, we offer exciting challenges and ample opportunities to showcase your talents. As a trusted and respected partner to the pharmaceutical industry, we uphold the highest standards in safety, quality and sustainability, while fostering a culture that empowers you to thrive. Join a rapidly expanding global company, where diverse perspectives and experiences come together in a collaborative environment. Here, you'll find a workplace that values both collective success and your individual contributions - offering long-term opportunities to grow and make an impact.

Your Role:

As a Senior Chemist R&D, you will play a key role in developing and optimizing robust chemical processes for clinical and commercial pharmaceutical products. Working within a multidisciplinary environment, you will combine scientific expertise, project leadership, and industrial mindset to deliver scalable and sustainable manufacturing solutions.

• Leading the development, optimization, and troubleshooting of chemical manufacturing processes.


• Supporting process scale-up and technology transfer from laboratory to pilot plant and commercial manufacturing.


• Driving continuous improvement initiatives to increase process robustness, efficiency, quality, and sustainability.


• Applying Quality by Design (QbD), Design of Experiments (DoE), Process Analytical Technology (PAT), and scientific data analysis to accelerate process understanding.


• Acting as the technical lead for customer projects, providing scientific expertise during client meetings and technical discussions.


• Collaborating closely with Process Research, Analytical Development, Production, Quality Assurance, Regulatory Affairs, Engineering, and HSE.


• Preparing technical documentation including development reports, risk assessments, technology transfer packages, and regulatory support documents.


• Identifying innovative technologies and new scientific approaches to strengthen process development capabilities.


• Mentoring junior scientists and sharing technical knowledge across the organization.


• Contributing to the strategic development of Process Development through innovation, operational excellence, and continuous improvement.

Your Profile:

• PhD or MSc in Organic Chemistry, Process Chemistry or a related scientific discipline.


• Significant experience (5+ years) in pharmaceutical process development, ideally within a CDMO or GMP manufacturing environment.


• Strong expertise in synthetic organic chemistry, reaction mechanisms, process optimization, and scale-up.


• Good knowledge of Design of Experiments (DoE), Quality by Design (QbD), Process Analytical Technology (PAT), and statistical data analysis.


• Experience supporting technology transfer from laboratory to pilot or commercial manufacturing.


• Solid understanding of GMP requirements and ICH guidelines.


• Excellent problem-solving and scientific reasoning skills.


• Strong communication and stakeholder management abilities, including customer interactions.


• Ability to manage multiple priorities while maintaining high scientific standards.


• Fluency in English and French.

Your Benefits:

• Free on-site parking


• Health insurance: up to 10% discount on supplementary health insurance through our partner providers


• Generous and flexible employee share purchase plan


• Child allowance: Siegfried AG supplements the statutory cantonal child allowance by 10% and provides an additional CHF 100 per month


• Individual learning and development opportunities


• REKA checks: employees benefit from a 20% discount on REKA holiday checks


• Attractive company pension plan


• On-site fitness classes and a wide range of company events


• Access to the Swibeco employee benefits platform


• 5 weeks of annual leave with the option to purchase up to 2 additional weeks of vacation

Founded in 1873 in Zofingen, Switzerland, Siegfried has grown into a global network of 16 sites across three continents. With a team of more than 4,200 highly skilled professionals, we take the innovations of our pharmaceutical customers to industrial scale and manufacture safe drugs for patients worldwide. As a fully integrated CDMO, Siegfried is one of the few organizations today that can carry out the development and manufacturing of APIs and finished dosage forms under one roof. This unique combination of know-how and experience makes us the most trusted partner in the pharmaceutical industry.