Associate Oligonucleotides Analytics (m/w/d)

Flexsis AG, Filiale Basel LS; Basel; Hybrid; CHF 75,000 - 110,000; Full time

Job summary

Flexsis AG, Filiale Basel LS, is assisting Roche in Basel to recruit an Associate Oligonucleotides Analytics (m/w/d). The role focuses on performing routine measurements for oligonucleotides (HPLC with UV and/or MS) and contributing to method development within a 5-person team.

Starting 01.12.2026 for a 1-year engagement with a possible extension, the position is based in Basel with a 100% workload and up to 10% remote work. Fluency in English is required; German is beneficial.

Qualifications

• Vocational chemical laboratory technician with 2–3 years in pharma.
• Hands-on with analytical instrumentation (HPLC, MS).
• Interest or background in oligonucleotide analytics.
• Strong LC-MS knowledge is a plus.
• Experience with large molecules/biologics analytics is an advantage.
• Self-motivated, team player with quality mindset.
• Good English; German proficiency is beneficial.

Responsibilities

• Perform routine measurements for Oligonucleotides (HPLC with UV and/or MS detection).
• Plan, execute, and document experiments in a 5-person team.
• Use Empower or OpenLab to control analytical instruments.
• Evaluate data with Genedata or Oligo Analysis Accelerator.
• Develop, improve, and validate analytical methods for oligonucleotides quality assessment.
• Ensure compliance with GxP guidelines and SOPs.

Skills

HPLC

Mass spectrometry

GxP knowledge

Quality mindset

Team player

English proficiency

Education

Chemistry lab technician apprenticeship

Tools

Empower

OpenLab

Genedata

Oligo Analysis Accelerator

Job description

Description of the company

Flexsis is a company of the Interiman Group, one of the leading providers of personnel services in Switzerland. Thanks to our solid expertise as well as the competencies within the Interiman Group, we offer tailored solutions in personnel consulting.

For our client Roche in Basel, we are looking for a reliable and motivated Associate Oligonucleotides Analytics (m/w/d).

General Information:

• Start Date: 01.12.2026
• Planned Duration of Employment: 1 year
• Extension: possible
• Workplace: Basel
• Workload: 100%
• Home Office: max. 10% remote

Role & Responsibilities

Tasks & Responsibilities:

• Performing routine measurements for Oligonucleotides (mainly HPLC with UV and/or Single Quad MS detection)
• Planning, executing, and documenting experiments collaboratively in a team of five associates.
• Use chromatographic data systems like Empower or OpenLab to control analytical instruments.
• Evaluate data with Genedata or Oligo Analysis Accelerator
• Developing, improving, and validating analytical methods for the quality assessment of Oligonucleotides.
• Ensuring compliance with GxP guidelines and relevant SOPs.

Candidate Profile

Must Haves:

• a vocational scientific qualification as chemical laboratory technician (e.g. apprenticeship) with at least 2-3 years experience in the pharmaceutical industry (No Studies Degree; No Master or PhD) (*****)
• Hands-on experience with analytical instrumentation and techniques (e.g., HPLC, MS) (*****)
• Interest or background in analytical development for oligonucleotides (*****)
• Strong knowledge of LC-MS applications and instruments is a plus
• Experience with large molecules/biologics analytics is an advantage
• Self-motivated, proactive, open-minded, goal-oriented, and a strong team player
• Stringent quality mindset, excellent attention to detail, and knowledge of GxP requirements across clinical phases.
• Good command of English; German proficiency is beneficial.