Associate Oligonucleotides Analytics (m/w/d) for F. Hoffmann La Roche in Basel

We make it GmbH; Basel; Hybrid; CHF 90,000 - 120,000; Full time

Job summary

Cybersteel Inc. in Basel is seeking a candidate for Analytical Research and Development in Pharma Technical Development, focusing on synthetic molecules. You will work on developing robust analytical methods for oligonucleotides and peptides, with hands-on HPLC, MS, and LC-MS expertise, and ensure GxP compliance and high data quality.

Strong English communication is essential. The role emphasizes lab work in a collaborative team and offers a standard 40-hour week with up to 10% remote work.

Qualifications

• 2–3 years of experience in the pharmaceutical industry with focus on analytical development for oligonucleotides or peptides.
• Hands-on experience with analytical instrumentation and techniques (HPLC, MS).
• Interest or background in analytical development for oligonucleotides.

Responsibilities

• Perform routine measurements for Oligonucleotides (HPLC with UV and/or MS).
• Plan, execute, and document experiments in a small team.
• Use Empower or OpenLab to control analytical instruments and evaluate data with Genedata or Oligo Analysis Accelerator.
• Develop, improve, and validate analytical methods for quality assessment of oligonucleotides.

Skills

HPLC

MS

LC-MS

English communication

GxP

Education

Vocational scientific qualification as chemical laboratory technician

Tools

Empower

OpenLab

Genedata

Oligo Analysis Accelerator

Job description

Cybersteel Inc.
376-293 City Road, Suite 600
San Francisco, CA 94102

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Jobs

Datum: 20.10.2026

We make it GmbH is a company operating nationally in Switzerland. Thanks to many years of successful experience, it has a high level of competence in the personnel services sector. Concentration of placement activities on the core areas of industry, technology, office/administration, engineering, pharmaceuticals and IT. We make it GmbH places the highest demands on quality, ethics and discretion.

For our customer, the company F. Hofmann La Roche, are we searching for:

Background

Behind each product in clinical trials or sold by Roche is the involvement of Pharma Global Technical Operations. Pharma Global Technical Operations makes medicines with more than 10'000 employees at sites around the world. \"Pharma Technical Development\" is a global organization with over two thousand people dedicated to the development of new medicines to meet patients' needs. We actively collaborate and develop creative technical solutions to expertly deliver the pipeline and supply high quality products to patients. The group excels in its work through innovation, teamwork, dedication, and mutual respect and contributes every single day to bring new therapies to life and hope to patients. \"Synthetic Molecules Technical Development\" (PTDC) brings a broad range of experience across drug substance, drug product, and analytical sciences, and collaborates closely with partners in research and early development, Pharma Technical Development, and Commercial. PTDC is responsible for the technical development of our synthetic molecules pipeline and the manufacture of clinical supplies for clinical studies.

The position on offer is located in Analytical Research and Development for Synthetic molecules within Pharma Technical Development. Analytical Development for synthetic molecules is responsible for the development of resource and cost-efficient analytical methods by use of state of the art and innovative techniques such as highperformance liquid chromatography, gas or ion chromatography or mass spectrometry. The ultimate goal of our work is the development of a robust control strategy to release products for clinical trials, and finally for commercial supply.

The Perfect Candidate (m/f/d): Has completed a vocational scientific qualification (e.g. apprenticeship, laboratory technician, Chemielaborant) and brings 2-3 years of experience in the pharmaceutical industry with a clear focus on analytical development for oligonucleotides or peptides. They offer strong hands-on expertise with HPLC, MS and ideally LC-MS, an excellent quality mindset with great attention to detail, and the ability to quickly adapt to new tools, ideas and agile ways of working while communicating confidently in English. This person should be motivated to focus on Lab Work.

Work hours

Working hours: Standard 40h / Week, max. 10% remote

Tasks

Performing routine measurements for Oligonucleotides (mainly HPLC with UV and/or Single Quad MS detection), Planning, executing, and documenting experiments collaboratively in a team of five associates, Use chromatographic data systems like Empower or OpenLab to control analytical instruments, Evaluate data with Genedata or Oligo Analysis Accelerator, Developing, improving, and validating analytical methods for the quality assessment of Oligonucleotidesm Ensuring compliance with GxP guidelines and relevant SOPs.

Qualifications

a vocational scientific qualification as chemical laboratory technician (e.g. apprenticeship) with at least 2-3 years experience in the pharmaceutical industry (No Studies Degree; No Master or PhD) (*****), Hands-on experience with analytical instrumentation and techniques (e.g., HPLC, MS) (*****), Interest or background in analytical development for oligonucleotides (*****), Strong knowledge of LC-MS applications and instruments is a plus, Experience with large molecules/biologics analytics is an advantage, Self-motivated, proactive, open-minded, goal-oriented, and a strong team player, Stringent quality mindset, excellent attention to detail, and knowledge of GxP requirements across clinical phases, Good command of English; German proficiency is beneficial.