Oligonucleotides Analytics Associate | HPLC/MS | Basel

Flexsis; Basel; Hybrid; CHF 85,000 - 110,000; Full time

Job summary

Flexsis, on behalf of Roche in Basel, seeks a reliable Associate Oligonucleotides Analytics to support development and quality assessment of oligonucleotides. Start date 01.12.2026, 100% workload, 1-year contract with possible extension, Basel workplace, up to 10% remote.

You will perform routine measurements (HPLC/UV, MS), plan and document experiments in a small team, operate Empower/OpenLab, and ensure GxP compliance. English is required; German helpful.

Qualifications

• Vocational scientific qualification as chemical laboratory technician with 2–3 years in the pharmaceutical industry.
• Hands-on experience with analytical instrumentation (HPLC, MS).
• Interest or background in analytical development for oligonucleotides.
• Strong knowledge of LC-MS applications.
• Experience with large molecules/biologics analytics is an advantage.
• Self-motivated, proactive, team player with quality mindset and attention to detail across clinical phases.
• Good command of English; German proficiency is beneficial.

Responsibilities

• Perform routine measurements for Oligonucleotides (HPLC with UV and/or MS detection).
• Plan, execute, and document experiments collaboratively in a team of five associates.
• Use chromatographic data systems (Empower or OpenLab) to control analytical instruments.
• Evaluate data with Genedata or Oligo Analysis Accelerator.
• Develop, improve, and validate analytical methods for quality assessment of Oligonucleotides.
• Ensure compliance with GxP guidelines and SOPs.

Skills

Oligonucleotide analytics

HPLC

Mass spectrometry

GxP knowledge

Team player

English good

German helpful

Education

Chemical laboratory technician apprenticeship

Tools

HPLC systems

MS instruments

Empower/OpenLab

Job description

Flexsis, on behalf of Roche in Basel, seeks a reliable Associate Oligonucleotides Analytics to support development and quality assessment of oligonucleotides. Start date 01.12.2026, 100% workload, 1-year contract with possible extension, Basel workplace, up to 10% remote.

You will perform routine measurements (HPLC/UV, MS), plan and document experiments in a small team, operate Empower/OpenLab, and ensure GxP compliance. English is required; German helpful.