Senior Research Scientist, Method Development (LC-MS)

Altasciences; Laval (administrative region); Hybrid; CAD 110,000 - 160,000; Full time

Benefits offered by this job

Health/Dental/Vision Insurance

RRSP matching

Paid Vacation & Holidays

Sick and Bereavement Leave

Employee Assistance & Telehealth

Job summary

Altasciences in Laval, QC seeks a Senior Research Scientist to lead the development and optimization of regulatory-ready LC-MS/MS bioanalytical methods for diverse modalities such as small molecules, peptides, biologics, biomarkers, and oligonucleotides.

The role requires 5–8+ years in LC-MS/MS bioanalysis, strong troubleshooting, and excellent written and verbal communication to guide project teams and client discussions.

Qualifications

• Master’s or PhD in Biochemistry/ Chemistry/ Analytical Chemistry (or related field).
• Typically 5–8+ years of LC-MS/MS bioanalysis experience and leading method development projects.
• Experience with sample preparation techniques (protein precipitation, SPE, immunoaffinity, enzymatic digestion).
• Strong scientific writing and communication skills for stakeholders.

Responsibilities

• Develop and optimize robust LC-MS/MS bioanalytical methods under regulatory standards.
• Lead sample preparation, analysis, and data interpretation to meet timelines.
• Troubleshoot complex bioanalytical challenges through systematic experimentation.
• Discuss method development strategies and results in client meetings.
• Prepare method development reports, SOPs, and other documentation.
• Collaborate with validation and operations for method transfer and implementation.
• Stay current with LC-MS technologies to drive continuous improvement.
• Adhere to Health and Safety protocols and lab upkeep.

Skills

LC-MS/MS

Bioanalysis

Method development

Regulatory compliance

Sample preparation

Data interpretation

Scientific writing

Team leadership

Education

Master’s or Ph.D. in Biochemistry/Chemistry/Analytical Chemistry

Tools

Mass spectrometry instrumentation

Job description

## Senior Research Scientist, Method Development (LC-MS)Apply: On-site: Laval, Quebec: Full time: Posted 2 Days Ago: R103083**About The Role**We are seeking a highly motivated and experienced Senior Research Scientist with strong expertise in bioanalytical mass spectrometry to join our Method Development team. The successful candidate will lead the development and optimization of regulatory-ready bioanalytical methods using liquid chromatography-mass spectrometry (LC-MS/MS) for a variety of therapeutic modalities, including small molecules, peptides, biologics, biomarkers, and oligonucleotides.**What You’ll Do Here*** Develop and optimize robust bioanalytical methods using LC-MS/MS in compliance with regulatory standards.* Perform and oversee sample preparation, analysis, and data interpretation while meeting project timelines and quality expectations.* Investigate and resolve complex bioanalytical challenges through systematic troubleshooting, experimental design, and root-cause assessment.* Participate in client discussions and scientific meetings, communicating method development strategies, analytical results, and technical recommendations.* Prepare, review, and approve method development reports, SOPs, and other technical documentation as required.* Collaborate with validation and operational teams to support successful method transfer and implementation.* Stay current with advancements in LC-MS technologies and best practices to support continuous improvement.* Adhere to Health and Safety protocols, including personal protective practices and laboratory upkeep.**What You’ll Need to Succeed*** Master’s or Ph.D. in Biochemistry, Chemistry, Analytical Chemistry, or a related discipline; a Bachelor’s degree with significant relevant experience may also be considered.* Typically 5-8+ years of relevant experience in LC-MS/MS bioanalysis, with demonstrated experience independently leading bioanalytical method development projects.* Experience in sample preparation techniques appropriate to the analyte type (e.g., protein precipitation, solid-phase extraction, immunoaffinity-based approaches, enzymatic digestion).* Strong scientific writing, communication, and presentation skills, with the ability to effectively communicate complex technical concepts to both scientific and non-scientific stakeholders.Altasciences strives to provide a French work environment for its employees in Quebec. Altasciences has taken all reasonable measures to avoid imposing the above language requirement. This requirement is essential for the position of **Senior Research Scientist, Method development (LCMS)** in particular, but without limitation, for the following reason(s):* The requirement to have study protocols read and documented in English as required by industry regulatory agencies**What We Offer**Altasciences offers a wide variety of benefits to help our employees live healthy and fulfilling lives both at and outside of work.**Altasciences’ Benefits Package Includes:*** Health/Dental/Vision Insurance Plans* 401(k)/RRSP with Employer Match* Paid Vacation and Holidays* Paid Sick and Bereavement Leave* Employee Assistance & Telehealth Program**Altasciences’ Incentive Programs Include:*** Training & Development Programs* Employee Referral Bonus Program* Annual Performance Reviews#LI-MB1### Your New Company!At Altasciences we all move in unison to assist and work in the discovery, development, and manufacturing of new drug therapies to get them faster to people who need them. No matter your role, we all play an important part and you will have a significant impact on the health and well-being of people across the globe. By living our values of Employee Development, Customer Focus, Quality and Excellence, Respect and Integrity, we look to foster a passionate and collaborative work environment and we are looking for talented and enthusiastic people, like you, to join our growing team! Whether you're a recent college graduate or seeking your next career opportunity, it's time to discover your future at Altasciences.We are better together and together We Are Altasciences.